Comparative Evaluation of the Effect of Hypericum Perforatum on Pain Level in the Treatment of Recurrent Aphthous Stomatitis:A Randomized Clinical Trial
Status: Recruiting
Location: See location...
Intervention Type: Combination product, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of the treatment of Recurrent Aphthous Stomatitis (RAS) is to accelerate the healing of ulcers by reducing pain and inflammation, thus enabling patients to perform their oral functions comfortably. It has been said many times in the literature that St. John's wort is very effective in wound healing.In this study, the evaluation of the therapeutic effects of St. John's wort extract on the clinical symptoms and ulcer healing rate in patients with Recurrent Aphthous Stomatitis (RAS), a condition with no definitive treatment, was aimed.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• 18 years and over
• Having a history of RAS for at least 2 years
• Having one in an easily accessible area in the mouth
• RAS has not exceeded a period of 48 hours
Locations
Other Locations
Turkey
Batman University
RECRUITING
Batman
Contact Information
Primary
Rojdan F GÜNEŞ UYSAL, PhD
rojdangunes@hotmail.com
05433796751
Backup
Giray G TEKİN, PhD
dt.giray@hotmail.com
05052601118
Time Frame
Start Date: 2025-02-01
Estimated Completion Date: 2025-04-15
Participants
Target number of participants: 75
Treatments
Active_comparator: group 1 Triamsinolon asetonid
% 0,1 Triamsinolon asetonid (Kenacort- A orabase pomad) will be used on ulcer areas 4 times a day (after meals and before going to bed) for 7 days.
Active_comparator: grup 2 Hyaluronic acid
Hyaluronic acid gel (Aftamed ® Oral gel, AktiFarma, Istanbul, Turkey) will be used on ulcer areas 4 times a day (after meals and before bedtime) for 7 days.
Experimental: grup 3 St. John's wort oil
St. John's wort oil (Zade Vital; Health\&Fitness, Developed With Ege University Argefar) will be used on ulcer areas 4 times a day (after meals and before going to bed) for 7 days.
Related Therapeutic Areas
Sponsors
Leads: Batman University