Aphthous Stomatitis
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Aphthous Stomatitis Overview

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What is the definition of Aphthous Stomatitis?
Aphthous stomatitis is a common condition characterized by recurrent round or oval painful ulcers, commonly known as canker sores, that appear in the mucous membranes of the mouth, such as the inside of the lips or cheeks, on the gums, in the soft palate, on the floor of the mouth, or on the tongue. In some individuals, recurrent aphthous ulcers may be associated with other serious health concerns.
What are the symptoms of Aphthous Stomatitis?
Symptoms of aphthous stomatitis usually begin with a sensation of burning discomfort one or two days before the ulcers appear (prodrome). The ulcer or ulcers usually first appear(s) as a round, yellow raised spot with a red halo that then develops into a painful ulceration that is attached to the mucosa by a white, yellow, or grey membrane.
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What are the current treatments for Aphthous Stomatitis?
There is no cure for aphthous stomatitis, and most minor ulcers heal within one to two weeks without treatment. Treatment for aphthous stomatitis is therefore focused on decreasing pain, improving healing, and preventing recurrences and includes local anesthetics, such as benzocaine; occlusive agents, such as bismuth subsalicylate, sucralfate, and 2-octyl cyanoacrylate; bioadherent emollient pastes; antiseptics, such as chlorhexidine gluconate and hydrogen peroxide; glucocorticosteroids, such as clobetasol, dexamethasone, fluocinonide, and triamcinolone; antimicrobials, such as tetracycline, doxycycline, or minocycline; honey; immunomodulatory drugs, such as amlexanox, colchicine, cyclosporine, cyclophosphamide, dapsone, methotrexate, montelukast, thalidomide, or retinoids; pentoxifylline; or quercetin. Other treatments may include the use of herbal remedies, tincture of benzoin, cautery with silver nitrate, laser therapy, and supplementation with iron, zinc, and vitamins B1, B2, B6, B12, or C.
Who are the top Aphthous Stomatitis Local Doctors?
Elite in Aphthous Stomatitis
Elite in Aphthous Stomatitis
Referral may be required
70, Bukowska St, 
Poznan, WP, PL 

Zuzanna Slebioda practices practicing medicine in Poznan, Poland. Ms. Slebioda is rated as an Elite expert by MediFind in the treatment of Aphthous Stomatitis. She is also highly rated in 7 other conditions, according to our data. Her clinical expertise encompasses Canker Sore, Aphthous Stomatitis, Lichen Planus, Glossitis, and Osteotomy.

Elite in Aphthous Stomatitis
Elite in Aphthous Stomatitis
Referral may be required
Rome, IT 

Donato Rigante practices practicing medicine in Rome, Italy. Mr. Rigante is rated as an Elite expert by MediFind in the treatment of Aphthous Stomatitis. He is also highly rated in 55 other conditions, according to our data. His clinical expertise encompasses PFAPA, Aphthous Stomatitis, Canker Sore, and Mevalonate Kinase Deficiency.

 
 
 
 
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Elite in Aphthous Stomatitis
Elite in Aphthous Stomatitis
Referral may be required
70, Bukowska St, 
Poznan, WP, PL 

Elzbieta Szponar practices practicing medicine in Poznan, Poland. Ms. Szponar is rated as an Elite expert by MediFind in the treatment of Aphthous Stomatitis. She is also highly rated in 2 other conditions, according to our data. Her clinical expertise encompasses Aphthous Stomatitis, Canker Sore, Sutton Disease 2, and Dermatitis Herpetiformis.

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What are the latest Aphthous Stomatitis Clinical Trials?
The Preventive and Therapeutic Effects of Spirulina Preparations on Recurrent Aphthous Ulcers of the Oral Mucosa
The Preventive and Therapeutic Effects of Spirulina Preparations on Recurrent Aphthous Ulcers of the Oral Mucosa
Enrollment Status: Recruiting
Publish Date: July 23, 2026
Intervention Type: Other, Dietary supplement
Study Phase: Not Applicable

Summary: This is a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the efficacy and safety of spirulina supplementation in patients with radiation-induced oral mucositis (RIOM) receiving radiotherapy for head and neck cancer. Participants will be randomly assigned to receive either spirulina tablets or placebo in addition to standard oral care during radiothera...

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Relief of Sore Throat Pain or Minor Mouth Lesions, Including Minor Aphthous Ulcers, in Children and Adults Treated With OROSEDAL: An Observational Study
Relief of Sore Throat Pain or Minor Mouth Lesions, Including Minor Aphthous Ulcers, in Children and Adults Treated With OROSEDAL: An Observational Study
Enrollment Status: Recruiting
Publish Date: June 02, 2026
Intervention Type: Device

Summary: This prospective, multicenter, national, observational, non-interventional post-market clinical follow-up study will evaluate the performance and safety of OROSEDAL in children and adults with sore throat or minor oral lesions, including minor aphthous ulcers and histologically confirmed oral lichen planus. OROSEDAL is prescribed in routine practice before inclusion. Patients will be followed for ...

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