Cardiopulmonary resuscitation (CPR) is an emergency maneuver used on a victim who is in cardiac arrest. Early and efficient CPR, with a focus on chest compressions, is a key element in increasing victim survival. The success of resuscitation does not only depend on the immediate initiation of the maneuvers, but also on the quality with which they are applied. However, there is an obvious gap in the knowledge of these maneuvers. This study aims to analyze the acquisition and retention/maintenance of cardiopulmonary resuscitation (CPR) skills and the impact of the use of technology and autonomous training in medical students.