Cardiac Arrest Clinical Trials

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The fMRI in CardiaC arrEst With Uncertain Prognosis (FACE-UP) Study

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

The goal of this observational study is to determine whether specific advanced MRI measures are associated with functional outcomes in patients who are comatose after cardiac arrest. The main question\[s\] it aims to answer are: Aim 1: Determine if stimulus-based functional MRI (fMRI)-measured activations are independently associated with favorable neurological outcomes after cardiac arrest Aim 2: Determine if resting state functional MRI (rs-fMRI)-measured functional network connectivity is independently associated with favorable neurological outcomes after cardiac arrest. Aim 3: Determine if diffusion tensor imaging (DTI)-measured white matter integrity is associated with favorable neurological outcomes after cardiac arrest. Participants will undergo advanced MRI sequences at time of clinical MRI, and will be followed for 6 months post-arrest.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• survive of an in or out of hospital cardiac arrest

Locations
United States
Massachusetts
Brigham and Women's Hospital
ACTIVE_NOT_RECRUITING
Boston
Brigham and Women's Hospital
RECRUITING
Brookline
Contact Information
Primary
Samuel B Snider, MD
ssnider@bwh.harvard.edu
857-307-2391
Time Frame
Start Date: 2024-05-16
Estimated Completion Date: 2027-12-01
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Leads: Brigham and Women's Hospital
Collaborators: American Heart Association

This content was sourced from clinicaltrials.gov