Hypothermia Versus Normothermia After Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital Cardiac Arrest: A Cluster Randomized Trial (SAVE-J NEUROTHERM Trial)
Status: Recruiting
Location: See all (28) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The SAVE-J NEUROTHERM trial is a cluster randomized trial that evaluated and compared the mortality risk, neurological outcomes, and adverse events between patients who underwent hypothermia and those who underwent normothermia after extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• OHCA
• Age of 18-75 years, known or estimated
• An initial cardiac arrest rhythm of ventricular fibrillation/pulseless ventricular tachycardia or pulseless electrical activity
Locations
Other Locations
Japan
Oshima Prefectural Hospital
RECRUITING
Amami
Asahikawa Medical University Hospital
NOT_YET_RECRUITING
Asahikawa
Ebina General Hospital
RECRUITING
Ebina
Hyogo Prefectural Kakogawa Medical Center
RECRUITING
Kakogawa
Kagawa University Hospital
RECRUITING
Kita-gun
Hyogo Emergency Medical Center
RECRUITING
Kobe
Kurume University Hospital
RECRUITING
Kurume
Kyoto Second Red Cross Hospital
NOT_YET_RECRUITING
Kyoto
Okayama University Hospital
RECRUITING
Okayama
Saitama Red Cross Hospital
RECRUITING
Saitama
Hokkaido University Hospital
RECRUITING
Sapporo
Sapporo Medical University Hospital
RECRUITING
Sapporo
Sendai Medical Center
RECRUITING
Sendai
Tohoku University Hospital
RECRUITING
Sendai
Okinawa Prefectural Nanbu Medical Center & Children's Medical Center
RECRUITING
Shimajiri-gun
Osaka Saiseikai Senri Hospital
RECRUITING
Suita
Institute of Science Tokyo Hospital
RECRUITING
Tokyo
Japanese Red Cross Musashino Hospital
RECRUITING
Tokyo
Keio University Hospital
RECRUITING
Tokyo
National Hospital Organization Disaster Medical Center
RECRUITING
Tokyo
Nippon Medical School Hospital
RECRUITING
Tokyo
St. Luke's International Hospital
RECRUITING
Tokyo
Tokyo Metropolitan Bokutoh Hospital
RECRUITING
Tokyo
Tokyo Metropolitan Tama Medical Center
RECRUITING
Tokyo
Tottori Prefectural Central Hospital
RECRUITING
Tottori-shi
Toyooka Public Hospital
RECRUITING
Toyooka
Tsuyama Chuo Hospital
RECRUITING
Tsuyama
Saiseikai Yokohamashi Tobu Hospital
RECRUITING
Yokohama
Contact Information
Primary
Akihiko Inoue
j-neuro@googlegroups.com
81-87-981-2392
Time Frame
Start Date: 2025-01-06
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 468
Treatments
Active_comparator: Normothermia
Temperature control at 36 °C
Experimental: Hypothermia
Temperature control at 33-34 °C
Related Therapeutic Areas
Sponsors
Leads: Kagawa University