Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest - A Randomized Clinical Trial
Status: Recruiting
Location: See all (6) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Out-of-hospital cardiac arrest
• Age ≥ 18 years
• ≥ 1 manual defibrillation attempt by emergency medical services
• Shockable rhythm as the last known rhythm
• Two manual defibrillators present on-site
Locations
Other Locations
Denmark
Emergency Medical Services, the North Denmark Region
RECRUITING
Aalborg
Danish Air Ambulance, Danish Regions
NOT_YET_RECRUITING
Aarhus N
Prehospital Emergency Medical Services, Central Denmark Region
RECRUITING
Aarhus N
Copenhagen Emergency Medical Services, the Capital Region of Denmark
NOT_YET_RECRUITING
Ballerup Municipality
The Prehospital Center, Region Zealand
NOT_YET_RECRUITING
Næstved
Emergency Medical Services, the Region of Southern Denmark
NOT_YET_RECRUITING
Vejle
Contact Information
Primary
Lars W Andersen
lwandersen@clin.au.dk
+4578414848
Backup
Bertram L Kirkegaard
bertramkirkegaard@clin.au.dk
Time Frame
Start Date: 2025-03-15
Estimated Completion Date: 2029-03-01
Participants
Target number of participants: 909
Treatments
Active_comparator: Anterior-lateral pad positioning
Experimental: Anterior-posterior pad positioning
Experimental: Double-sequential defibrillation
Anterior-lateral pad positioning combined with anterior-posterior pad positioning for a total of 4 pads and 2 shocks.
Related Therapeutic Areas
Sponsors
Collaborators: University of Aarhus
Leads: Lars Wiuff Andersen