Pediatric Resuscitation Neuroprognostication and Outcomes Registry

Status: Recruiting
Location: See all (7) locations...
Study Type: Observational
SUMMARY

The goal of this observational study is to understand the long-term outcomes of children in the Netherlands who experience cardiac arrest, either in or outside of the hospital. The main questions it aims to answer are: What are the survival rates and neurological outcomes in children after cardiac arrest? What types of emergency and post-resuscitation care are provided, and how do they impact long-term recovery? How do children and their families function over time after the event? Researchers will analyze data from routine medical records and follow patients through standard outpatient visits. No extra procedures will be required beyond normal care. For those who survive to hospital discharge, additional follow-up data will be collected with consent. Participants will: Be children under 18 years old who have had a cardiac arrest and were treated in one of the seven participating academic hospitals Have their routine medical care data collected anonymously Be invited (if surviving) for follow-up visits at 3, 12, and 24 months post-arrest and at specific ages (5, 8, 12, and 17 years) to assess physical and psychological recovery

Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 day
Maximum Age: 18
Healthy Volunteers: f
View:

• Pediatric patients under the age of 18

• Experienced in-hospital or out-of-hospital cardiac arrest in the Netherlands

• Attended by emergency medical services or admitted to one of the seven participating Dutch academic pediatric hospitals

• Cardiac arrest defined as absence of palpable pulse or need for chest compressions lasting ≥1 minute

• Arrest managed under European Resuscitation Council guidelines (BLS/APLS)

Locations
Other Locations
Netherlands
Amsterdam UMC
RECRUITING
Amsterdam
UMCG
RECRUITING
Groningen
LUMC
RECRUITING
Leiden
MUMC
RECRUITING
Maastricht
Radboud umc
RECRUITING
Nijmegen
Erasmus MC
RECRUITING
Rotterdam
UMCU
RECRUITING
Utrecht
Contact Information
Primary
Gabry De Jong
gabry.dejong@erasmusmc.nl
0031107040704
Backup
Marijn Albrecht, MD
m.albrecht@erasmusmc.nl
0031107040704
Time Frame
Start Date: 2023-06-14
Estimated Completion Date: 2030-01
Participants
Target number of participants: 500
Treatments
Pediatric cardiac arrest patient
The study cohort consists of pediatric patients under the age of 18 who have experienced a cardiac arrest-either in-hospital (IHCA) or out-of-hospital (OHCA)-in the Netherlands. Eligible patients must have received care from emergency medical services (EMS) or been admitted to one of the seven participating academic pediatric hospitals following the arrest.~Cardiac arrest is defined as the absence of a palpable pulse or the need for chest compressions lasting at least one minute, in line with European Resuscitation Council guidelines. Both basic life support (BLS) and advanced pediatric life support (APLS) protocols apply.
Related Therapeutic Areas
Sponsors
Collaborators: UMC Utrecht, UMCG, Zoll Medical Corporation, Amsterdam UMC, Radboud University Medical Center, Maastricht University Medical Center, Stichting Vermeer14, Leiden University Medical Center
Leads: Matthijs de Hoog

This content was sourced from clinicaltrials.gov