Cardiac Arrest Clinical Trials

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Utilizing Artificial Intelligence to Optimize Chest Compression Region During Cardio-pulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest.

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Procedure, Device
Study Type: Observational
SUMMARY

The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations. Current guidelines recommend a standardized compression point (the lower half of the sternum), yet recent research indicates that this position can compress the aortic valve in approximately 48.7% of patients, significantly reducing the chances of successful resuscitation. This study will develop a deep learning model based on YOLO v8 to analyze real-time arterial pressure waveforms to identify proper aortic valve opening and closing. By identifying specific waveform features that humans cannot easily distinguish, the AI will guide rescuers to adjust the compression site-typically toward the left ventricle-to ensure optimal blood output. The project seeks to transform CPR from a standardized one-size-fits-all approach into a personalized, precision medicine intervention.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:

• Adults aged 20 years or older.

• Patients with out-of-hospital cardiac arrest (OHCA) undergoing 3.cardiopulmonary resuscitation (CPR) in the emergency department.

⁃ Cardiac arrest caused by non-traumatic factors.

Locations
Other Locations
Taiwan
Far Eastern Memorinal Hospital
RECRUITING
New Taipei City
Contact Information
Primary
Sheng-En Chu, physician
ianchu300@msn.com
886-2-7728-1843
Time Frame
Start Date: 2025-01-06
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 255
Treatments
OHCA Patients Receiving AI-Enhanced Resuscitation.
Adult patients (20 years or older) with non-traumatic Out-of-Hospital Cardiac Arrest (OHCA) who receive Advanced Life Support (ALS) at the Far Eastern Memorial Hospital Emergency Department. This cohort provides the data for AI training (Years 1-2) and participates in the clinical validation of the AI-guided compression technique (Year 3).
Related Therapeutic Areas
Sponsors
Leads: Far Eastern Memorial Hospital
Collaborators: National Health Research Institutes, Taiwan

This content was sourced from clinicaltrials.gov