Condition 101 About Cardiogenic Shock

What is the definition of Cardiogenic Shock?

Cardiogenic shock takes place when the heart has been damaged so much that it is unable to supply enough blood to the organs of the body.

What are the alternative names for Cardiogenic Shock?

Shock - cardiogenic

What are the causes for Cardiogenic Shock?

The most common causes are serious heart conditions. Many of these occur during or after a heart attack (myocardial infarction). These complications include:

  • A large section of heart muscle that no longer moves well or does not move at all
  • Breaking open (rupture) of the heart muscle due to damage from the heart attack
  • Dangerous heart rhythms, such as ventricular tachycardia, ventricular fibrillation, or supraventricular tachycardia
  • Pressure on the heart due to a buildup of fluid around it (pericardial tamponade)
  • Tear or rupture of the muscles or tendons that support the heart valves, especially the mitral valve
  • Tear or rupture of the wall (septum) between the left and right ventricles (lower heart chambers)
  • Very slow heart rhythm (bradycardia) or problem with the electrical system of the heart (heart block)
Heart

Cardiogenic shock occurs when the heart is unable to pump as much blood as the body needs. It can happen even if there hasn't been a heart attack if one of these problems occurs and your heart function drops suddenly.

What are the symptoms for Cardiogenic Shock?

Symptoms include:

  • Chest pain or pressure
  • Coma
  • Decreased urination
  • Fast breathing
  • Fast pulse
  • Heavy sweating, moist skin
  • Lightheadedness
  • Loss of alertness and ability to concentrate
  • Restlessness, agitation, confusion
  • Shortness of breath
  • Skin that feels cool to the touch
  • Pale skin color or blotchy skin
  • Weak (thready) pulse

What are the current treatments for Cardiogenic Shock?

Cardiogenic shock is a medical emergency. You will need to stay in the hospital, most often in the Intensive Care Unit (ICU). The goal of treatment is to find and treat the cause of shock to save your life.

You may need medicines to increase blood pressure and improve heart function, including:

  • Dobutamine
  • Dopamine
  • Epinephrine
  • Levosimendan
  • Milrinone
  • Norepinephrine
  • Vasopressin

These medicines may help in the short-term. They are not often used for a long time.

When a heart rhythm disturbance (dysrhythmia) is serious, urgent treatment may be needed to restore a normal heart rhythm. This may include:

  • Electrical "shock" therapy (defibrillation or cardioversion)
  • Implanting a temporary pacemaker
  • Medicines given through a vein (IV)

You may also receive:

  • Pain medicine
  • Oxygen
  • Fluids, blood, and blood products through a vein (IV)

Other treatments for shock may include:

  • Cardiac catheterization with coronary angioplasty and stenting
  • Heart monitoring to guide treatment
  • Heart surgery (coronary artery bypass surgery, heart valve replacement, left ventricular assist device)
  • Intra-aortic balloon counterpulsation (IABP) to help the heart work better
  • Pacemaker
  • Ventricular assist device or other mechanical support

What is the outlook (prognosis) for Cardiogenic Shock?

In the past, the death rate from cardiogenic shock ranged from 80% to 90%. In more recent studies, this rate has decreased to 50% to 75%.

When cardiogenic shock is not treated, the outlook is very poor.

What are the possible complications for Cardiogenic Shock?

Complications may include:

  • Brain damage
  • Kidney damage
  • Liver damage

When should I contact a medical professional for Cardiogenic Shock?

Go to the emergency room or call the local emergency number (such as 911) if you have symptoms of cardiogenic shock. Cardiogenic shock is a medical emergency.

How do I prevent Cardiogenic Shock?

You may reduce the risk of developing cardiogenic shock by:

  • Quickly treating its cause (such as heart attack or heart valve problem)
  • Preventing and treating the risk factors for heart disease, such as diabetes, high blood pressure, high cholesterol and triglycerides, or tobacco use

REFERENCES

Felker GM, Teerlink JR. Diagnosis and management of acute heart failure. In: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier; 2019:chap 24.

Hollenberg SM. Cardiogenic shock. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 99.

Latest Advances On Cardiogenic Shock

  • Condition: Heart Attack with Cardiogenic Shock
  • Journal: BioMed research international
  • Treatment Used: Intra-Aortic Balloon Counterpulsation
  • Number of Patients: 1962
  • Published —
The aim of this study was to explore the preference, effect, and outcomes of intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock patients.
  • Condition: Acute Coronary Syndrome
  • Journal: PloS one
  • Treatment Used: Combined Glycoprotein IIb/IIIa Inhibitor and Ticagrelor Therapies
  • Number of Patients: NULL
  • Published —
The study researched the outcomes of combined glycoprotein IIb/IIIa inhibitor therapy with ticagrelor for patients with acute coronary syndrome.

Clinical Trials For Cardiogenic Shock

Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 3
  • Intervention Type: Drug
  • Participants: 206
  • Start Date: March 2021
LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock Patients
Clinical Trial
  • Status: Not yet recruiting
  • Participants: 400
  • Start Date: March 2021
Cangrelor in Patients With Acute Myocardial Infarction Undergoing PCI After CPR, Ventilated or Cardiogenic Shock