Fabry Cardiomyopathy: Identification of Early Myocardial Structural and Tissue Abnormalities Using Multiparametric MRI
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study will evaluate whether cardiac MRI T1 and T2 mapping improves our ability to detect early abnormalities in the heart in patients with Fabry disease and identify patients at increase risk of adverse events.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Fabry disease;
• Age ≥ 18 years.
Locations
Other Locations
Canada
University Health Network
RECRUITING
Toronto
Contact Information
Primary
Kate Hanneman
kate.hanneman@uhn.ca
416-323-6400
Time Frame
Start Date: 2021-06-15
Estimated Completion Date: 2029-03-31
Participants
Target number of participants: 300
Treatments
Other: Cardiac MRI, ECG and Blood Biomarkers
Additional sequences will be performed during routine clinical cardiac MRI and additional blood samples will be collected during routine blood work.
Authors
Kate Hanneman
Related Therapeutic Areas
Sponsors
Collaborators: IRCCS Policlinico S. Donato, Libin Cardiovascular Institute of Alberta, Alberta Health services, Icahn School of Medicine at Mount Sinai, The Cleveland Clinic, Vancouver Coastal Health, Vancouver General Hospital
Leads: University Health Network, Toronto