Understanding and Characterizing the Genetics of Patients With Arrhythmia-Induced Cardiomyopathy

Status: Recruiting
Location: See all (4) locations...
Study Type: Observational
SUMMARY

The goal of this observational study is to learn about the genetic insights of arrhythmya-induced cardiomyopathy and its clinical prognosis. The main questions it aims to answer are: I. Does patients with arrhythmia-induced cardiomyopathy have a greater proportion of genetic mutations compared with other types of cardiomyopathy or general population? II. Have the genetics any prognostic impact in patients with arrhythmia-induced cardiomyopathy?

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Presence of atrial fibrillation or atrial flutter not self-limited.

• Performance of a cardiac imaging test with systolic function analysis (echocardiogram, magnetic resonance, CT scan) during the clinical course of the arrhythmia, exhibiting a left ventricular ejection fraction (LVEF) \<50%. In order for the test to be representative, the maximum time between the performance of the imaging test and the rhythm control procedure will be 3 months, in the absence of intervening cardiovascular events that may have caused a variation in LVEF. In the event that the patient had a previously known LVEF \<50%, the change with respect to this attributable to tachyarrhythmia has to be ≥10%.

• Signature of informed consent.

• Ability to understand and accept participation in the study.

Locations
Other Locations
Spain
Albacete University Hospital Complex
NOT_YET_RECRUITING
Albacete
Ciudad Real General University Hospital
RECRUITING
Ciudad Real
12 de Octubre University Hospital
RECRUITING
Madrid
Ramón y Cajal University Hospital
ACTIVE_NOT_RECRUITING
Madrid
Contact Information
Primary
Martín Negreira-Caamaño, MD, PhD
martin.negcam@gmail.com
+34913908000
Backup
Daniel Rodríguez-Muñoz, MD, PhD
daniel.rodriguez.mnz@gmail.com
+34913908000
Time Frame
Start Date: 2024-12-01
Estimated Completion Date: 2026-12
Participants
Target number of participants: 109
Treatments
A
Patients with arrhytmia-induced cardiomyopathy criteria
B
Patients without arrhytmia-induced cardiomyopathy criteria
Related Therapeutic Areas
Sponsors
Leads: Hospital Universitario 12 de Octubre

This content was sourced from clinicaltrials.gov