Caroli Disease
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Caroli Disease Overview

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Learn About Caroli Disease

What is the definition of Caroli Disease?
Caroli disease is a condition characterized by an abnormal widening of the intrahepatic bile ducts (the ducts that carry bile from the liver) and renal cysts. People affected by this condition experience recurrent episodes of cholestasis, stone development in the bile ducts, and bacterial cholangitis. In addition to the symptoms of Caroli disease, people affected by Caroli syndrome may also experience liver fibrosis and portal hypertension (high blood pressure of the portal vein). Although the underlying cause of Caroli disease and Caroli syndrome are poorly understood, they are thought to be genetic conditions. Caroli disease generally occurs sporadically in people with no family history of the condition; however, rare reports exist of autosomal dominant inheritance in association with autosomal dominant polycystic kidney disease. Caroli syndrome is generally inherited in an autosomal recessive manner and is frequently seen in association with autosomal recessive polycystic kidney disease.
What are the alternative names for Caroli Disease?
  • Caroli disease
  • Caroli disease isolated
  • Congenital polycystic dilatation of intrahepatic bile ducts
  • Cystic dilatation of the intrahepatic biliary tree
Who are the top Caroli Disease Local Doctors?
Elite in Caroli Disease
Yasunori Sato
Elite in Caroli Disease
Yasunori Sato
Tokyo, JP 

Yasunori Sato practices practicing medicine in Tokyo, Japan. Sato is rated as an Elite expert by MediFind in the treatment of Caroli Disease. They are also highly rated in 30 other conditions, according to our data. Their clinical expertise encompasses Caroli Disease, Cholangiocarcinoma (Bile Duct Cancer), Primary Biliary Cholangitis, Gamma Knife Radiosurgery, and Osteotomy.

Elite in Caroli Disease
Dr. Mario Strazzabosco
Internal Medicine
Elite in Caroli Disease
Dr. Mario Strazzabosco
Internal Medicine

Yale New Haven Hospital

20 York St, 
New Haven, CT 
203-737-6060
Experience:
44+ years
Languages Spoken:
English
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Mario Strazzabosco is a primary care provider, practicing in Internal Medicine in New Haven, Connecticut. He has been practicing medicine for over 44 years. Dr. Strazzabosco is rated as an Elite provider by MediFind in the treatment of Caroli Disease. He is also highly rated in 16 other conditions, according to our data. His clinical expertise encompasses Congenital Hepatic Fibrosis, Cholangiocarcinoma (Bile Duct Cancer), Caroli Disease, Liver Transplant, and Hepatectomy.

 
 
 
 
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Elite in Caroli Disease
Rene Fahrner
Elite in Caroli Disease
Rene Fahrner
Thun, BE, CH 

Rene Fahrner practices practicing medicine in Thun, Switzerland. Fahrner is rated as an Elite expert by MediFind in the treatment of Caroli Disease. They are also highly rated in 5 other conditions, according to our data. Their clinical expertise encompasses Caroli Disease, Bile Duct Cysts, Appendicitis, Hepatectomy, and Appendectomy.

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What are the latest Caroli Disease Clinical Trials?
Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource (ARPKD Database Study)
Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource (ARPKD Database Study)
Enrollment Status: Recruiting
Publish Date: June 13, 2025

Summary: Hepato-renal fibrocystic diseases (HRFD) is a term developed that encompasses rare diseases such as Autosomal Recessive Polycystic Kidney Disease (ARPKD), and other diseases with common features (Joubert syndrome, Bardet Biedl syndrome, Meckel-Gruber syndrome, congenital hepatic fibrosis (CHF), Caroli syndrome (CS), polycystic liver disease, oro-facial-digital syndrome, nephronophithisis (NPHP), a...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center