Ocular Perfusion in Patients With Unilateral Carotid Artery Stenosis

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

The aim of the presented study is to evaluate ocular blood flow, respectively optic nerve head blood flow in patients with carotid artery stenosis before and after carotid endarterectomy or carotid artery stenting. Additionally, the investigators aim to compare optic nerve head blood flow in patients with CAS and healthy age- and sex-matched control subjects. Furthermore, the investigators intend to evaluate brain tissue oxygenation in patients with carotid artery stenosis before, during and after CEA and carotid artery stenting. Finally, the investigators will assess potential correlations between LSFG and NIRS results in patients with unilateral carotid artery stenosis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:

• Men and Women aged ≥ 18 years

• Signed informed consent

• Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant

• Diagnosis of unilateral carotid artery stenosis and scheduled carotid endarterectomy or carotid artery stenting

• Men and Women aged ≥ 18 years

• Signed informed consent

• Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant

• Normal findings in the medical history, unless the investigator considers an abnormality to be clinically irrelevant

• Non-Smokers

Locations
Other Locations
Austria
Department of Clincal Pharmacology, Medical University of Vienna
RECRUITING
Vienna
Contact Information
Primary
Gerhard Garhöfer, Assoc. Prof. Priv. Doz. MD
klin-pharmakologie@meduniwien.ac.at
+43 1 40400 29880
Time Frame
Start Date: 2024-04-09
Estimated Completion Date: 2026-05-02
Participants
Target number of participants: 45
Treatments
Carotid endarterectomy (CEA) (Group 1)
Subjects with unilateral carotid artery stenosis and planned CEA
Carotid artery stenting (Group 2)
Subjects with unilateral carotid artery stenosis and planned carotid artery stenting
Healthy Control Group (Group 3)
Healthy age- and sex-matched control subjects
Related Therapeutic Areas
Sponsors
Leads: Medical University of Vienna

This content was sourced from clinicaltrials.gov