Latest Advances

  • Condition: Kaposi Sarcoma (KS)-Associated Herpesvirus (KSHV)-Associated Multicentric Castleman Disease (MCD)
  • Journal: Blood advances
  • Treatment Used: High-Dose Zidovudine with Valganciclovir (AZT/VGC), Rituximab, or Rituximab with Liposomal Doxorubicin (R-Dox)
  • Number of Patients: 62
  • Published —
This study evaluated treatments for Kaposi sarcoma (KS)-associated herpesvirus (KSHV)-associated multicentric Castleman disease (MCD) in people living with HIV (PLWH).
  • Condition: Idiopathic Multicentric Castleman Disease (iMCD)
  • Journal: Journal of medical case reports
  • Treatment Used: Interleukin-6 Blockade
  • Number of Patients: 2
  • Published —
This case report discusses patients diagnosed with idiopathic multicentric Castleman disease (lymph gland inflammation; iMCD) treated with interleukin-6 blockade.
  • Condition: Unicentric Castleman Disease
  • Journal: Blood advances
  • Treatment Used: Surgical Excision
  • Number of Patients: 116
  • Published —
The study researched the outcomes of Unicentric Castleman disease with multicentric Castleman disease-like inflammatory state.
  • Condition: TAFRO Syndrome
  • Journal: Annals of hematology
  • Treatment Used: Tocilizumab
  • Number of Patients: 31
  • Published —
This review of the literature investigated the effectiveness of tocilizumab, an anti-interleukin-6 receptor antibody, in patients with TAFRO syndrome.
  • Condition: HHV8-Positive Castleman's Disease
  • Journal: Cell transplantation
  • Treatment Used: Allogeneic Hematopoietic Stem Cell Transplantation
  • Number of Patients: 1
  • Published —
The study researched the safety and effectiveness of allogeneic hematopoietic stem cell transplantation for treating HHV8-positive Castleman's disease.
  • Condition: TAFRO (Thrombocytopenia, Anasarca, Fever, Reticulin Myelofibrosis or Renal Dysfunction and Organomegaly)
  • Journal: BMJ case reports
  • Treatment Used: Corticosteroids, Tocilizumab and Rituximab
  • Number of Patients: 1
  • Published —
The study researched a case of TAFRO (thrombocytopenia, anasarca, fever, reticulin myelofibrosis or renal dysfunction and organomegaly).
  • Condition: Intrathoracic Unicentric Castleman's Disease
  • Journal: BMC surgery
  • Treatment Used: Thoracic Surgery, Video-Assisted
  • Number of Patients: 10
  • Published —
The study researched the outcomes of video-assisted thoracoscopic surgery is a safe and effective method to treat intrathoracic unicentric Castleman's disease.
  • Condition: Acute Kidney Injury caused by TAFRO Syndrome
  • Journal: Kidney & blood pressure research
  • Treatment Used: Long-Term Corticosteroids Combined with Bortezomib and Cyclophosphamide
  • Number of Patients: 1
  • Published —
The study researched the outcomes of a case of acute kidney injury caused by TAFRO syndrome.
  • Condition: Castleman disease in Children
  • Journal: Orphanet journal of rare diseases
  • Treatment Used: Surgery, Medications, and/or Radiation
  • Number of Patients: 23
  • Published —
The study researched Castleman disease in children.
  • Condition: Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Failure, and Organomegaly (TAFRO) Syndrome with Bilateral Adrenal Hemorrhage
  • Journal: The American journal of case reports
  • Treatment Used: Chemotherapy
  • Number of Patients: 2
  • Published —
The study researched the outcomes of two cases of thrombocytopenia, anasarca, fever, reticulin fibrosis/renal failure, and organomegaly (TAFRO) syndrome with bilateral adrenal hemorrhage.
  • Condition: TAFRO Syndrome
  • Journal: Zhonghua yi xue za zhi
  • Treatment Used: CHOP Chemotherapy, Glucocorticoid, and Glucocorticoid Combined with Rituximab or Tocilizumab
  • Number of Patients: 6
  • Published —
This study explored the clinical characteristics, treatment, and prognosis of TAFRO syndrome (a variant of Castleman's disease).
  • Condition: Castleman Disease (CD) with Different Types of Thoracic Involvement
  • Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
  • Treatment Used: Mass Resection, Chemotherapy, and Immunomodulatory Therapy
  • Number of Patients: 30
  • Published —
This study sought to improve understanding of Castleman disease (CD) with different types of thoracic involvement, including current treatment strategies.
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