Condition 101 About Cat Scratch Disease

What is the definition of Cat Scratch Disease?

Cat scratch disease (CSD) is a bacterial infection that primarily affects the lymph nodes. It is typically caused by the bacteria bartonella (Bartonella henselae). It is usually transmitted by being scratched or bitten by a cat, but rarely, no scratch or bite is involved. Symptoms frequently include the formation of a small bump at the site of the scratch or bite, followed by fever and swollen lymph nodes (lymphadenopathy) within 1-3 weeks. Lymphadenopathy commonly resolves on its own within a few months, but in some cases it may persist for up to 2 years. People with weakened immune systems (and less commonly, people with healthy immune systems) may develop more widespread disease and additional symptoms or neurological complications, which can be severe. In most cases, particularly in children and adolescents, having CSD once means that it cannot occur again. The recurrence of symptoms months after disease onset has been reported in a few adults with CSD. Treatment in mild or moderate cases typically involves medicines or strategies to improve symptoms, such as using fever reducers, pain relievers, or local heat over the affected lymph node(s). In more severe or systemic cases, management may involve lymph node aspiration and/or antibiotics.

What are the alternative names for Cat Scratch Disease?

  • Bartonellosis due to Bartonella henselae infection
  • Cat scratch fever

What are the symptoms for Cat Scratch Disease?

Most people with cat scratch disease have been bitten or scratched by a cat and develop a mild infection at the point of injury within about 3-14 days. The infected area may be warm and painful and may appear appear swollen and red with round, raised lesions. Lymph nodes, especially those around the head, neck, and upper limbs, become swollen. Additionally, a person with cat scratch disease may experience fever, headache, fatigue, achiness and discomfort (malaise), sore throat, enlarged spleen, and/or loss of appetite.

Latest Advances On Cat Scratch Disease

  • Condition: Cat Scratch Disease
  • Journal: Journal of clinical pharmacy and therapeutics
  • Treatment Used: Azithromycin and Rifampin
  • Number of Patients: 1
  • Published —
In this case study, researchers sought to determine the best treatment for cat scratch disease in a child.
  • Condition: Cervicofacial granulomatous lymphadenitis in children
  • Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • Treatment Used: Surgical excision
  • Number of Patients: 40
  • Published —
The study researched long-term outcomes of surgical excision for cervicofacial granulomatous lymphadenitis in children.

Clinical Trials For Cat Scratch Disease

Clinical Trial
  • Status: Recruiting
  • Phase: Phase 3
  • Intervention Type: Drug
  • Participants: 100
  • Start Date: May 31, 2017
Intra-nodal Injection of Gentamicin for the Treatment of Suppurated Cat Scratch Disease's Lymphadenitis: A Randomized Controlled Study