Catecholaminergic Polymorphic Ventricular TachycardiaSymptoms, Doctors, Treatments, Advances & More
Learn About Catecholaminergic Polymorphic Ventricular Tachycardia
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition characterized by an abnormal heart rhythm (arrhythmia). As the heart rate increases in response to physical activity or emotional stress, it can trigger an abnormally fast heartbeat called ventricular tachycardia. Episodes of ventricular tachycardia can cause light-headedness, dizziness, and fainting (syncope). In people with CPVT, these episodes typically begin in childhood.
CPVT most commonly results from mutations in two genes, RYR2 and CASQ2. RYR2 gene mutations cause about half of all cases, while mutations in the CASQ2 gene account for up to 5 percent of cases. Mutations in other genes are rare causes of the condition.
The prevalence of CPVT is estimated to be about 1 in 10,000 people. However, the true prevalence of this condition is unknown.
When CPVT results from mutations in the RYR2 gene, it follows an autosomal dominant inheritance pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In about half of cases, an affected person inherits an RYR2 gene mutation from one affected parent. The remaining cases result from new (de novo) mutations in the RYR2 gene that occur during the formation of reproductive cells (eggs or sperm) in an affected individual's parent or in early embryonic development. These cases occur in people with no history of the disorder in their family.
Intermountain Health Heart & Vascular - 201 West Park Cardiology
Originally from New Albany, Indiana, Dr. Moore earned his undergraduate degree in Physics at Indiana University, where he also completed a Doctor of Medicine and a residency in Internal Medicine. He went on to train at the University of Pittsburgh Medical Center, completing fellowships in Cardiovascular Disease and Clinical Cardiac Electrophysiology. Dr. Moore returned to his home state of Indiana and built a successful data-driven electrophysiology program, focusing on innovative care for patients with atrial fibrillation. He relocated to Grand Junction in 2019, bringing a wealth of experience and his style of patient-centered care to the Western Slope. Dr. Moore’s clinical interests include arrhythmia management, cardiac ablation, left atrial appendage closure, cardiac rhythm management devices and hybrid atrial fibrillation ablation.“I am passionate about helping patients understand their issues and options. I will help you to understand your cardiac rhythm issues and weigh options for treatment.”Married to his college sweetheart for more than 20 years, Dr. Moore has two children, two dogs and two cats. His hobbies include camping, hiking, skiing and paddleboarding on lakes and rivers. Dr. Moore is rated as a Distinguished provider by MediFind in the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia. He is also highly rated in 27 other conditions, according to our data. His clinical expertise encompasses Familial Progressive Cardiac Conduction Defect, Atrial Fibrillation, Ventricular Tachycardia, Pacemaker Implantation, and Cardiac Ablation. Dr. Moore is board certified in American Board Of Internal Medicine , American Board Of Internal Medicine , and American Board Of Internal Medicine. Dr. Moore is currently accepting new patients.
Atrium Health Sanger Heart & Vascular Institute Kenilworth
John Fedor is a Cardiologist and a Cardiac Electrophysiologist practicing medicine in Charlotte, North Carolina. Dr. Fedor is rated as a Distinguished provider by MediFind in the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia. He is also highly rated in 26 other conditions, according to our data. His clinical expertise encompasses Arrhythmias, Sick Sinus Syndrome, Familial Ventricular Tachycardia, Pacemaker Implantation, and Cardiac Ablation. Dr. Fedor is board certified in American Board Of Internal Medicine, American Board Of Internal Medicine, Cardiovascular Disease, and American Board Of Internal Medicine, Clinical Cardiac Electrophysiology. Dr. Fedor is currently accepting new patients.
Atrium Health Sanger Heart & Vascular Institute Kenilworth
Brian Powell is a Cardiologist and a Cardiac Electrophysiologist practicing medicine in Charlotte, North Carolina. Dr. Powell is rated as a Distinguished provider by MediFind in the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia. He is also highly rated in 21 other conditions, according to our data. His clinical expertise encompasses Arrhythmias, Sick Sinus Syndrome, Cardiomyopathy, Pacemaker Implantation, and Cardiac Ablation. Dr. Powell is board certified in American Board Of Internal Medicine, American Board Of Internal Medicine, Cardiovascular Disease, and American Board Of Internal Medicine, Clinical Cardiac Electrophysiology. Dr. Powell is currently accepting new patients.
Published Date: July 01, 2020
Published By: National Institutes of Health