Learn About Celiac Disease
Celiac disease is a condition in which the immune system is abnormally sensitive to gluten, a protein found in wheat, rye, and barley. Celiac disease is an autoimmune disorder; autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs. Without a strict, lifelong gluten-free diet, inflammation resulting from immune system overactivity may cause a wide variety of signs and symptoms involving many parts of the body.
The risk of developing celiac disease is increased by certain variants of the HLA-DQA1 and HLA-DQB1 genes. These genes provide instructions for making proteins that play a critical role in the immune system. The HLA-DQA1 and HLA-DQB1 genes belong to a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria.
Celiac disease is a common disorder. Its prevalence has been estimated at about 1 in 100 people worldwide.
Celiac disease tends to cluster in families. Parents, siblings, or children (first-degree relatives) of people with celiac disease have between a 4 and 15 percent chance of developing the disorder. However, the inheritance pattern is unknown.
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Alberto Tapia is a Gastroenterologist in Cleveland, Ohio. Dr. Tapia is rated as an Elite provider by MediFind in the treatment of Celiac Disease. His top areas of expertise are Celiac Disease, Malabsorption, Diarrhea, Tropical Sprue, and Endoscopy.
Cleveland Clinic Main Campus
Claire Jansson is a Gastroenterologist in Cleveland, Ohio. Dr. Jansson has been practicing medicine for over 16 years and is rated as an Elite provider by MediFind in the treatment of Celiac Disease. Her top areas of expertise are Celiac Disease, Malabsorption, Lactose Intolerance, Liver Embolization, and Colonoscopy.
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Benjamin Lebwohl is a Gastroenterologist in New York, New York. Dr. Lebwohl is rated as an Elite provider by MediFind in the treatment of Celiac Disease. His top areas of expertise are Celiac Disease, Malabsorption, Diarrhea, Colonoscopy, and Endoscopy.
Summary: This randomized controlled trial aims to evaluate the effect of a navigator nurse-supported mobile application, developed based on the Information-Motivation-Behavioral Skills (IMB) model, on the quality of life of adult patients newly diagnosed with celiac disease. Participants will be randomized into intervention and control groups. The intervention group will use the mobile application with nav...
Summary: Hashimoto's thyroiditis is an autoimmune condition that reduces functioning of the thyroid gland and can lead to a substantial decline in quality of life for patients, with impacted patients often describing unremitting brain fog, fatigue/malaise and weight gain leading to difficulty functioning in their jobs and homes. It is the most common cause of hypothyroidism in the U.S. and affects up to 10...
Published Date: April 01, 2019
Published By: National Institutes of Health