The Efficacy of Remimazolam on Incidence of Hypoxia During Sedated Transvaginal Oocyte Retrieval: A Multicenter Randomized Controlled Trial.
Status: Recruiting
Location: See all (3) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Hypoxia is the most common adverse reaction during sedation outside the operating room.Exploring novel drug combinations to reduce the incidence of hypoxia during sedation in patients undergoing transvaginal oocyte retrieval procedures enhances patient safety and lowers perioperative adverse event rates. This multicenter, prospective, randomized, controlled clinical study will compare the hypoxia incidence rate of the remimazolam-alfentanil combination against the commonly used propofol-alfentanil combination.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: f
View:
• Subjects aged 18 to 50 years planning to undergo painless oocyte retrieval
• Subjects classified as American Society of Anesthesiologists (ASA) physical status I-II
Locations
Other Locations
China
Dongyang People's Hospital
NOT_YET_RECRUITING
Dongyang
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING
Hangzhou
Lishui People's Hospital
NOT_YET_RECRUITING
Lishui
Contact Information
Primary
Diansan Su, Dr.
diansansu@yahoo.com
+86-18616514088
Backup
Shuhan Gu, MD.
shuhangu@foxmail.com
+86-13515813047
Time Frame
Start Date: 2025-10-20
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 400
Treatments
Active_comparator: propofol-alfentanil
Sedation using remimazolam-alfentanil
Experimental: remimazolam-alfentanil
Sedation using remimazolam-alfentanil
Related Therapeutic Areas
Sponsors
Leads: Diansan Su