Infertility means you cannot get pregnant (conceive).
There are 2 types of infertility:
Inability to conceive; Unable to get pregnant
Many physical and emotional factors can cause infertility. It may be due to problems in the woman, man, or both.
Female infertility may occur when:
Female infertility may be caused by:
Male infertility may be due to:
Male infertility can be caused by:
Healthy couples under age 30 who have sex regularly will have about a 20% per month chance of getting pregnant each month.
A woman is most fertile in her early 20s. The chance a woman can get pregnant drops greatly after age 35 (and especially after age 40). The age when fertility starts to decline varies from woman to woman.
Infertility problems and miscarriage rates increase significantly after 35 years of age. There are now options for early egg retrieval and storage for women in their 20's. This will help ensure a successful pregnancy if childbearing is delayed until after age 35. This is an expensive option. However, women who know they will need to delay childbearing may consider it.
Treatment depends on the cause of infertility. It may involve:
Couples can increase the chances of becoming pregnant each month by having sex at least every 2 days before and during ovulation.
Ovulation occurs about 2 weeks before the next menstrual cycle (period) starts. Therefore, if a woman gets her period every 28 days the couple should have sex at least every 2 days between the 10th and 18th day after her period starts.
Having sex before ovulation occurs is especially helpful.
Women who are under or overweight may increase their chances of becoming pregnant by getting to a healthier weight.
Many people find it helpful to take part in support groups for people with similar concerns. You can ask your provider to recommend local groups.
As many as 1 in 5 couples diagnosed with infertility eventually become pregnant without treatment.
Most couples with infertility become pregnant after treatment.
Call your provider if you are not able to get pregnant.
Preventing STIs, such as gonorrhea and chlamydia, may reduce your risk of infertility.
Maintaining a healthy diet, weight, and lifestyle may increase your chance of getting pregnant and having a healthy pregnancy.
Avoiding the use of lubricants during sex may help improve sperm function.
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Broekmans FJ, Fauser BCJM. Female infertility: evaluation and management. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 132.
Catherino WH. Reproductive endocrinology and infertility. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 223.
Lobo RA. Infertility: etiology, diagnostic evaluation, management, prognosis. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 42.
Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile female: a committee opinion. Fertil Steril. 2015;103(6):e44-e50. PMID: 25936238 pubmed.ncbi.nlm.nih.gov/25936238/.
Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile male: a committee opinion. Fertil Steril. 2015;103(3):e18-e25. PMID: 25597249 pubmed.ncbi.nlm.nih.gov/25597249/.