Cerebral Palsy Clinical Trials

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Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This randomized controlled trial aims to compare the effectiveness of Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) versus CIMT alone in improving upper limb function, reducing spasticity, and enhancing functional independence in children with cerebral palsy (CP). A total of 46 children aged 3 to 15 years with spastic or dyskinetic cerebral palsy will be recruited from rehabilitation centers and hospitals in Sukkur, Pakistan. Participants will be randomly assigned into two groups: Group A will receive CIMT combined with FES, while Group B will receive CIMT alone. Both groups will undergo supervised therapy sessions five times per week for six weeks. Outcomes will be assessed before and after treatment using the Modified Ashworth Scale (MAS), Melbourne Assessment of Unilateral Upper Limb Function (MUUL), and Pediatric Evaluation of Disability Inventory (PEDI). The study aims to determine whether combining FES with CIMT provides greater improvements in motor recovery and daily functional performance in children with CP.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 15
Healthy Volunteers: f
View:

• Children aged 3 to 15 years, including both male and female population. Diagnosed with cerebral palsy (CP), confirmed by medical assessment and clinical evaluation.

• Moderate to severe impairment in upper limb function (as determined by a relevant motor function assessment scale, e.g., the Modified Ashworth Scale.

• Children with spastic and dyskinetic types of cerebral palsy. Children with cognitive ability that allows for participation in therapy, as determined by minimental status examination.

• No history of recent interventions (e.g., surgery, Botox injections) that may interfere with study participation.

Locations
Other Locations
Pakistan
Hira medical center Sukkur
RECRUITING
Lahore
Contact Information
Primary
Muhammad Hafeezullah Tariq, MSPPT
mangihafeezullah7@gmail.com
03140029255
Backup
Montiha Azeem, MSPTN
muntahaazeem9@gmail.com
03479717317
Time Frame
Start Date: 2026-05-18
Estimated Completion Date: 2026-06-29
Participants
Target number of participants: 46
Treatments
Experimental: group A CIMT Combined with FES Group
Participants in this group will receive Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) for the affected upper limb. Therapy will be conducted five sessions per week for six weeks, with each session lasting 60 minutes. CIMT will involve restraining the unaffected upper limb using a mitt or sling to encourage use of the affected limb during task-oriented activities such as reaching, grasping, releasing, drawing, stacking, and object manipulation. Functional Electrical Stimulation will be applied to targeted upper limb muscles including wrist extensors and finger muscles using therapeutic stimulation parameters to facilitate voluntary motor control and neuromuscular re-education.
Active_comparator: group B CIMT Alone Group
Participants in this group will receive Constraint-Induced Movement Therapy (CIMT) alone for six weeks, five sessions per week, with each session lasting 60 minutes. The unaffected upper limb will be restrained using a mitt or sling to encourage repetitive use of the affected upper limb during functional and task-specific activities. Activities will include self-care tasks, play-based exercises, grasp and release training, drawing, stacking blocks, and object handling exercises tailored to the child's functional level. No electrical stimulation will be administered in this group.
Related Therapeutic Areas
Sponsors
Leads: Montiha Azeem

This content was sourced from clinicaltrials.gov