MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial (METEOR-CRATR)
Status: Recruiting
Location: See location...
Intervention Type: Other, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-related data (imaging, dosimetry, clinical) before, during, and after treatment with definitive-intent chemoradiotherapy for patients with locally advanced cervical and pancreatic cancer.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Confirmation of intent to receive radiotherapy for one of the following diagnoses:
‣ Cervical cancer
⁃ Pancreatic cancer
• ECOG performance status ≤ 2
• At least 18 years old
• Able to understand and willing to sign an IRB-approved written informed consent document
Locations
United States
Missouri
Washington University School of Medicine
RECRUITING
St Louis
Contact Information
Primary
Cliff Robinson, M.D.
clifford.robinson@wustl.edu
314-362-8567
Time Frame
Start Date: 2024-01-11
Estimated Completion Date: 2032-12-31
Participants
Target number of participants: 60
Treatments
Other: Cervical Cancer
* Patients will have blood and tumor collected at various time points throughout participation in the study.~* Patients will have standard of care imaging obtained at various time points and a diffusion basis spectrum imaging (DBSI) MRI will be obtained at the end of standard of care MRI.
Other: Pancreatic Cancer
* Patients will have blood and tumor collected at various time points throughout participation in the study.~* Patients will have standard of care imaging obtained at various time points and a diffusion basis spectrum imaging (DBSI) MRI will be obtained at the end of standard of care MRI.
Related Therapeutic Areas
Sponsors
Leads: Washington University School of Medicine
Collaborators: National Cancer Institute (NCI)