Cervical Cancer Clinical Trials

Find Cervical Cancer Clinical Trials Near You

Personalized Risk-based Follow-up of Cervical Cancer Screening in Practice (PREDICT), Randomized Control Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this PREDICT is to assess a personalize approach to screening and management of cervical cancer testing. The investigators will evaluate patients who are due for a follow up cervical cancer screening in the primary care clinics in the Massachusetts General Brigham system. Patients will be randomized by clinic into three different arms (Arm 1: standard care, Arm 2: visit based reminders, Arm 3: visit based reminders and population health outreach)

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 21
Maximum Age: 70
Healthy Volunteers: f
View:

• have a cervix and are 21-70 years old

• receive care at a participating primary care practice (i.e. PCP team visit within past 3 years)

• have had a Pap and/ or HPV test within the past 3.5 years

• has a CCSM result that suggest a 5-year risk of developing CIN3+ that warrants surveillance at 1 or 3 years, diagnostic colposcopy, or treatment (i.e., above average risk).

⁃ Inclusion of those up to age 70 is intended to identify individuals whose prior history does not meet screening exit criteria, and warrants surveillance or diagnostic care even though women with adequate prior screening can stop at age 65

Locations
United States
Massachusetts
Massachusetts General Brigham
RECRUITING
Boston
Contact Information
Primary
Jennifer S Hass, MD
Jennifer.Haas@mgh.harvard.edu
617-724-1832
Backup
Amy J Wint, MSc
awint@mgh.harvard.edu
Time Frame
Start Date: 2026-07-22
Estimated Completion Date: 2029-01-22
Participants
Target number of participants: 7500
Treatments
No_intervention: Arm 1: Standard Care
Patients will receive the usual care provided by their PCP, practice, and/or specialist.
Active_comparator: Arm 2: Visit Based Reminder
Visit based reminders for physicians and patients that will be seen in Epic and Patient Gateway
Active_comparator: Arm 3: Population Health Outreach
Visit based reminders for physicians and patients that will be seen in Epic and Patient Gateway. Patients will received outreach from a population health coordinator. Patients will be sent educational materials, a reminder letter, and if needed, additional help scheduling their follow up appointment.
Related Therapeutic Areas
Sponsors
Leads: Massachusetts General Hospital

This content was sourced from clinicaltrials.gov