Assessing Personalized Vaginal Microbiome Contributions to HPV-driven Pre-malignant and Malignant Cervical Cancer
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 25
Maximum Age: 70
Healthy Volunteers: t
View:
• Age 25-70
• Attended the clinic for a Pap smear or colposcopy
Locations
Other Locations
Israel
Hadassah Medical Center
RECRUITING
Jerusalem
Contact Information
Primary
Ahinoam Lev Sagie, MD
levsagie@netvision.net.il
+972-54-4327178
Backup
Lilah Tsaitlin Mor, MD
lilah.tsaitlin@gmail.com
+972-54-7753434
Time Frame
Start Date: 2022-11-09
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 90
Treatments
Controls
Healthy women without HPV in their cervical and vaginal sample
Women with HPV
Women with HPV, with or without cervical intraepithelial neoplasia or carcinoma
Related Therapeutic Areas
Sponsors
Leads: Hadassah Medical Organization