Learn About Chiari Malformation Type 2

What is the definition of Chiari Malformation Type 2?
Chiari malformation type 2 (CM type II) is a type of Chiari malformation in which both the cerebellum and brain stem tissue extend into the foramen magnum (the hole at the skull base for passing of the spinal cord). CM type II is usually accompanied by a myelomeningocele (a form of spina bifida that occurs when the spinal canal and backbone do not close before birth), which can result in partial or complete paralysis of the area below the spinal opening. While the severity of CM type II can vary greatly, it can potentially cause serious complications during infancy or childhood. The exact cause of CM type II is not known but it appears to be due to defects in the brain and spinal cord that occur during fetal development.
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What are the alternative names for Chiari Malformation Type 2?
  • Chiari malformation type 2
  • Arnold Chiari malformation type II
  • Arnold-Chiari malformation
  • Chiari malformation type II
  • Chiari type II malformation
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What are the latest Chiari Malformation Type 2 Clinical Trials?
A Prospective Natural History Study of Patients With Syringomyelia

Background: Syringomyelia is a disorder in which a cyst (syrinx) forms within the spinal cord and causes spinal cord injury, with symptoms worsening over many years, including paralysis, loss of sensation, and chronic pain. Researchers are interested in obtaining more knowledge about how a syrinx forms in order to develop safer and more effective treatments for syringomyelia and related conditions. The goal o...

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In Utero Endoscopic Correction of Myelomeningocele: Laparotomy Versus Percutaneous - A Pilot Study

Summary: The purpose of this study is to evaluate the feasibility of a fetoscopic surgical technique for antenatal correction of fetal myelomeningocele. Two surgical approaches will be utilized. The percutaneous approach will be offered to participants with a posterior placenta. The laparotomy/uterine exteriorization approach will be offered to participants regardless of placental location.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Chiari Malformation Type 2?
Various manifestation of Chiari I malformation in children and improvement after surgery.
Myofascial Flap Closure Decreases Complications in Complex Surgery of the Craniocervical Junction in Ehlers-Danlos Patients.
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Hemifacial spasm secondary to Chiari malformation type I: Systematic review with case illustration.