Cholera Control in Endemic Regions of Africa: Clinical Surveillance and Cholera Shedding Study in the Context of Mass Vaccination Campaigns, Democratic Republic of the Congo

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This project aims to fill this essential knowledge gap by assessing the impact of oral cholera vaccine mass campaigns in 2 sites (urban and rural) in DRC, described in this protocol. The evidence generated from this project will be key to develop future strategies regarding cholera vaccine use in endemic settings, including places with higher burden in terms of cholera mortality.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• All patients presenting at the time of the study to any selected Cholera Treatment Center/Cholera Treatment Unit (CTC/CTU), matching the case definition and giving his/her consent (or assent for children 8 to 17 years old) to participate in the study will be eligible.

⁃ present to any selected CTC/CTU, match the case definition, participate to the clinical surveillance activity and test positive to RDT OR

⁃ Be a household member of a person respecting inclusion criteria 1. AND for whom the head of the household has provided verbal consent to participate AND giving his/her consent (or assent for children 8 to 17 years old) to participate in the study will be eligible.

Locations
Other Locations
Democratic Republic of the Congo
Anais Broban
RECRUITING
Goma
Contact Information
Primary
Anais BROBAN
anais.broban@epicentre.msf.org
+33140215494
Backup
Flavio Finger
flavio.finger@epicentre.msf.org
Time Frame
Start Date: 2021-05-11
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 6000
Related Therapeutic Areas
Sponsors
Collaborators: Wellcome Trust, Médecins Sans Frontières, France, Ministry of Public Health, Democratic Republic of the Congo, Grand Labo de Lubumbashi, Institut National de Recherche Biomédicale. Goma, République Démocratique du Congo
Leads: Epicentre

This content was sourced from clinicaltrials.gov

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