Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The findings from previous recent randomized controlled trials of The Cholera Hospital Based Intervention for 7 Days (CHoBI7) demonstrated that this intervention was effective in significantly reducing symptomatic cholera infections, diarrheal disease, and stunting among young children in intervention households, and had significant sustained impacts on handwashing with soap behaviors and improved water quality 12 months post intervention. Therefore, the investigators next step in the transition to scale is to: (1) To tailor the CHoBI7 program for delivery in rural health facilities and market test the CHoBI7 Program to determine the feasibility of providing a modified water, sanitation, and hygiene (WASH) package with only a soapy water bottle and chlorine tablets in both urban and rural settings through formative research and engagement of key stakeholders (Formative Research Phase); and (2) To evaluate the effectiveness of delivering the CHoBI7 program in district hospitals and sub-district health complexes in rural areas in terms of increases in WASH behaviors and decreases in diarrheal disease by conducting a randomized controlled trial (RCT) (Intervention Implementation and Evaluation Phase).

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: t
View:

• Diarrhea patients presenting with three or more loose stools over a 24h period

• Having no running water inside of the patient's home

• Plan to reside in current residence for the next 3 months

• Have a child \<5 years in the patient's household

• Have a working mobile phone in the household

Locations
Other Locations
Bangladesh
Manikganjg Sadar (District) Hospital
RECRUITING
Mānikganj
Contact Information
Primary
Christine Marie George, PhD
cmgeorge@jhu.edu
(202) 657-5798
Backup
Tahmina Parvin, MS
tahminaph14@yahoo.com
Time Frame
Start Date: 2024-08-19
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 1600
Treatments
Active_comparator: Standard Recommendation
Standard recommendation given by government of Bangladesh on the use of oral rehydration solution (ORS) and a flyer on water treatment and handwashing with soap given at the health facility during the time of diarrhea patient treatment.
Experimental: CHoBI7 Scale-Up Program
Health promoter delivery of handwashing with soap, water treatment, and safe water storage module in the health facility to diarrhea patients and the patient's household members during the time of treatment. This module includes video testimonials from diarrhea patient households on how the patient benefits from adhering to the promoted behaviors, and a demonstration on how to construct homemade handwashing washing stations. This in-person module is reinforced by weekly voice, interactive voice response, and text messages for three months sent to the mobile phones of diarrhea patient household members from a doctor at diarrhea ward at local hospital.
Related Therapeutic Areas
Sponsors
Collaborators: Research Training and Management International (RTMI), GiveWell, United States Agency for International Development (USAID)
Leads: Johns Hopkins Bloomberg School of Public Health

This content was sourced from clinicaltrials.gov