Learn About Chondroblastoma

What is the definition of Chondroblastoma?
Chondroblastoma, also known as Codman’s tumor, is a very rare non-cancerous bone tumor that develops in the cartilage, appears more often in male children and young adults, and mainly affects the ends of long bones near the growth plate in the arm, hip, or knee. Although chondroblastoma is a benign tumor, it can still spread (metastasize) to the lungs.
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What are the symptoms of Chondroblastoma?
The symptoms of chondroblastoma depend on the tumor’s location, with pain in the shoulder, hip, or knee joint being the most frequent symptom, followed by a wasting or shrinking (atrophy) of the muscle near the affected bone, decreased mobility of the associated joint, and fluid buildup surrounding the affected bone. Additional symptoms may include joint swelling or stiffness and limping.
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What are the current treatments for Chondroblastoma?
The pain associated with chondroblastoma may be initially treated with over-the-counter acetaminophen and ibuprofen. However, a chondroblastoma will continue to grow, so the main treatment is surgical removal of the tumor, usually by curettage (scraping of tumor), to prevent damage to the growth plate of the bone. In addition to removal of the tumor, surgical treatment for chondroblastoma may include bone grafting, bone cement, the use of plates or screws, or reconstruction of a damaged joint. After surgery, physical therapy is necessary to improve joint strength and function, as well as long-term follow-up to monitor for tumor recurrence. If a chondroblastoma cannot be removed with surgery, non-surgical treatments may include radiofrequency ablation, cryotherapy, or both. Chondroblastoma that has spread to the lungs is treated with surgical removal of the affected area or organ, which usually provides a cure.
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What are the latest Chondroblastoma Clinical Trials?
An Open-label, Multi-center, Phase 2 Study of Denosumab in Subjects With Giant Cell Rich Tumors of Bone

Summary: An open-label, multi-center, phase 2 study of the efficacy of denosumab in subjects with giant cell rich tumors of bone. The population will consist of subjects with the following tumor types: aneurysmal bone cysts (ABC), giant cell granuloma (GCG) and other giant cell rich lesions (primary bone, non-malignant).

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What are the Latest Advances for Chondroblastoma?
Rare chondroblastoma of the 6th left rib, video-assisted thoracoscopy resected: one case report and literature review.
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