Learn About Chondrosarcoma

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What is the definition of Chondrosarcoma?
Chondrosarcoma is a rare, slow-growing form of bone cancer that develops in the bones or the cartilage. The cartilage is the connective tissue from which most bones develop. Chondrosarcomas appear in bones or cartilage at the base of the skull, arms, scapula, ribs, pelvis, knee, femur (thighbone), or tibia.
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What are the symptoms of Chondrosarcoma?
Symptoms of chondrosarcoma depend on the cartilage or bone that is involved and include the appearance of a large mass on the affected bone, swelling and pressure surrounding the mass, muscle wasting, gradually increasing pain not relieved with rest, constant pain that worsens at night, and fracture of the affected bone. A chondrosarcoma that appears on the spine may cause weakness, numbness, and an inability to control the release of urine (incontinence) or bowels.
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What are the current treatments for Chondrosarcoma?
Treatment for chondrosarcoma depends on a patient’s age, overall health, medical history, the stage and location of the cancer, and may include surgery to remove the tumor, bone reconstructive surgery, amputation, radiation therapy, chemotherapy, and physical therapy.
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What are the latest Chondrosarcoma Clinical Trials?
A Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Chondrosarcoma and Clear Cell Sarcoma

Summary: This phase II trial studies how well atezolizumab works in treating patients with chondrosarcoma or clear cell sarcoma that is newly diagnosed, cannot be removed by surgery (unresectable), or has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of ...

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A Randomized, Blinded, Placebo-controlled, Phase 2 Study of INBRX-109 in Unresectable or Metastatic Conventional Chondrosarcoma

Summary: Randomized, blinded, placebo-controlled, Phase 2 study of INBRX-109 in unresectable or metastatic conventional chondrosarcoma patients.

What are the Latest Advances for Chondrosarcoma?
Intralesional curettage and cementation of low-grade chondrosarcomas of the appendicular skeleton: Long-term results from a single center.
Efficacy and safety of carbon ion radiotherapy for bone sarcomas: a systematic review and meta-analysis.
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Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man.