Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease
The purpose of this study is to assess feasibility, acceptability, and safety of providing transcranial direct current stimulation( tDCS) to Huntingtons Disease (HD) patients in the early to middle stages and to assess the efficacy of tDCS for HD-related behavioral, cognitive and other symptoms
⁃ confirmed HD mutation carriers and/or established family history alongside typical symptoms (i.e. chorea) of HD;
⁃ early (stages 1 and 2) or moderate (stage 3) stages according to Shoulson-Fahn
⁃ exhibit mild to moderate behavioral symptoms defined by severity scores in the PBA-S between 1 and 3 for any of the evaluated symptoms and no symptoms with a severity score of 4
⁃ stable doses of medications for at least one month
⁃ Have a caregiver willing to be present during tDCS sessions and answer questionnaires.
• willingness to participate in the study