Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain
Status: Recruiting
Location: See location...
Intervention Type: Other, Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Chronic widespread pain (CWP) is a common chronic pain condition in youth and often associated with significant pain-related and psychosocial impairment. Understanding the neurobiological mechanisms that may underlie pediatric chronic pain and pain-related impairment can inform future treatments to ameliorate patients' suffering, making it a critical area of empirical investigation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 11
Maximum Age: 17
Healthy Volunteers: t
View:
• Between ages 11-17 years
• Referred to the Boston Children's Hospital Pain Treatment Service for evaluation of a CWP condition with duration \> 3 months
• Right-handed
• Between ages 11-17 years
• Right-handed
Locations
United States
Massachusetts
Boston Children's Hospital
RECRUITING
Boston
Contact Information
Primary
Sarah Nelson, PhD
sarah.nelson@childrens.harvard.edu
6173557040
Time Frame
Start Date: 2021-11-04
Estimated Completion Date: 2024-08-31
Participants
Target number of participants: 70
Treatments
Other: Study Arm
All participants enrolled in the study will undergo baseline fMRI and baseline and follow-up (4-month post-baseline) assessment of stress physiology (i.e., allostatic load). Treatment as usual information will be gathered for all participants to assess observational intervention response.
Related Therapeutic Areas
Sponsors
Collaborators: National Center for Complementary and Integrative Health (NCCIH)
Leads: Boston Children's Hospital