Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain - Phase II
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Transcranial Alternating Current Stimulation (tACS), sham and Transcranial random noise stimulation (tRNS)
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: t
View:
• Meet the MRI / EEG screening criteria
• Fluent in English
Locations
United States
Texas
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Contact Information
Primary
Wen Li, PhD
Wen.Li.1@uth.tmc.edu
(713) 486-2700
Backup
Jada Malveaux
Jada.Malveaux@uth.tmc.edu
(713) 486-2700
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2028-02-29
Participants
Target number of participants: 60
Treatments
Experimental: tACS then tRNS then sham
Experimental: tACS then sham then tRNS
Experimental: tRNS then tACS then sham
Experimental: tRNS then sham then tACS
Experimental: Sham then tRNS then tACS
Experimental: Sham then tACS then tRNS
Related Therapeutic Areas
Sponsors
Leads: The University of Texas Health Science Center, Houston
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)