Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Behavioral, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of the study is to determine if an adapted mobile cognitive behavioral therapy (CBT) app (WebMAP Onc) is more effective than standard pain education in reducing chronic pain and improving daily functioning in adolescent survivors of pediatric cancer. This randomized study led by St. Jude Children's Research Hospital will involve 204 participants (102 adolescent survivors and 102 caregivers) across four U.S. hospitals. Outcomes include pain reduction, improved function, and the role of social determinants of health. Assessments occur at baseline, post-treatment, and 3-month follow-up.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 10
Maximum Age: 17
Healthy Volunteers: f
View:

• Adolescent Participants

‣ 10-17-year-old survivors of childhood cancer or those who received cancer directed therapies (e.g., Langerhan's Histiocytosis)

⁃ At least one-year post treatment completion

⁃ Pain present for 3 months or longer

⁃ Pain interfering with at least one area of daily functioning

• Parent/Caregiver Participants

‣ ≥ 18 years of age

⁃ Legally authorized to provide informed consent for the adolescent participant

Locations
United States
Tennessee
St. Jude Children's Research Hospital
RECRUITING
Memphis
Contact Information
Primary
Tara Brinkman, PhD
referralinfo@stjude.org
901-595-3300
Backup
Tara Brinkman
referralinfo@stjude.org
8662785833
Time Frame
Start Date: 2025-09-05
Estimated Completion Date: 2029-02
Participants
Target number of participants: 204
Treatments
Experimental: Arm I (mobile CBT)
Participants who are randomized to receive mobile CBT for chronic pain.
Sham_comparator: Arm II (Patient education)
Participants who are randomized to receive educational materials about chronic pain.
Related Therapeutic Areas
Sponsors
Leads: St. Jude Children's Research Hospital

This content was sourced from clinicaltrials.gov