Chronic Recurrent Multifocal Osteomyelitis
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Chronic Recurrent Multifocal Osteomyelitis Overview

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Learn About Chronic Recurrent Multifocal Osteomyelitis

What is the definition of Chronic Recurrent Multifocal Osteomyelitis?
Chronic recurrent multifocal osteomyelitis (CRMO) causes abnormal inflammation to occur in and around the bones. Symptoms usually begin in childhood but can occur at any age. Symptoms may include episodes of pain and joint swelling, skin redness, and sometimes a fever. In some cases, CRMO leads to abnormal bone growth, bone deformity, and fractures. CRMO may occur alone or with other skin or bowel inflammation conditions. In rare cases, CRMO occurs as part of one of these genetic syndromes: Majeed syndrome, DIRA or PAPA syndrome. The cause of CRMO is unknown, but a genetic influence is thought to be involved. Diagnosis of CRMO is based on the symptoms, clinical exam, and imaging studies. Other more common conditions may need to be excluded before a diagnosis of CRMO can be made.
What are the alternative names for Chronic Recurrent Multifocal Osteomyelitis?
  • Chronic recurrent multifocal osteomyelitis
  • CMO
  • CNO/CRMO
  • CRMO
  • Chronic multifocal osteomyelitis
  • Chronic nonbacterial osteomyelitis/Chronic recurrent multifocal osteomyelitis
  • Multifocal osteomyelitis, chronic
Who are the top Chronic Recurrent Multifocal Osteomyelitis Local Doctors?
Advanced in Chronic Recurrent Multifocal Osteomyelitis
Dr. Dima A. Youssef
Infectious Disease
Advanced in Chronic Recurrent Multifocal Osteomyelitis
Dr. Dima A. Youssef
Infectious Disease
Referral may be required

Medical Education Assistance Corporation

Bldg 52 Lake Dr, 
Mountain Home, TN 
423-439-8000
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Dima Youssef is an Infectious Disease provider practicing medicine in Mountain Home, Tennessee. Dr. Youssef is rated as an Advanced provider by MediFind in the treatment of Chronic Recurrent Multifocal Osteomyelitis. She is also highly rated in 22 other conditions, according to our data. Her clinical expertise encompasses Cellulitis, Infective Endocarditis, Lymphangitis, and Hospital-Acquired Pneumonia. Dr. Youssef is board certified in American Board Of Internal Medicine.

Advanced in Chronic Recurrent Multifocal Osteomyelitis
Dr. Wael E. Shams
Infectious Disease
Advanced in Chronic Recurrent Multifocal Osteomyelitis
Dr. Wael E. Shams
Infectious Disease
Referral may be required

ETSU Physicians & Associates- Infectious Disease

615 N State Of Franklin Rd, 
Johnson City, TN 
423-930-8337
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Wael Shams is an Infectious Disease provider practicing medicine in Johnson City, Tennessee. Dr. Shams is rated as an Advanced provider by MediFind in the treatment of Chronic Recurrent Multifocal Osteomyelitis. He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Osteomyelitis, Osteomyelitis in Children, Lymphangitis, and Methicillin-Resistant Staphylococcus Aureus (MRSA). Dr. Shams is board certified in American Board Of Internal Medicine.

 
 
 
 
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Elite in Chronic Recurrent Multifocal Osteomyelitis
Christian M. Hedrich
Elite in Chronic Recurrent Multifocal Osteomyelitis
Christian M. Hedrich
Referral may be required
Eaton Road, 
Liverpool, ENG, GB 

Christian Hedrich practices practicing medicine in Liverpool, United Kingdom. Mr. Hedrich is rated as an Elite expert by MediFind in the treatment of Chronic Recurrent Multifocal Osteomyelitis. He is also highly rated in 11 other conditions, according to our data. His clinical expertise encompasses Chronic Recurrent Multifocal Osteomyelitis, Osteomyelitis, Osteomyelitis in Children, and Systemic Lupus Erythematosus (SLE).

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What are the latest Chronic Recurrent Multifocal Osteomyelitis Clinical Trials?
Reliability and Validation of the WB-MRI Radiological Score in CRMO: Retrospective Observational Study in Paediatric Patients
Reliability and Validation of the WB-MRI Radiological Score in CRMO: Retrospective Observational Study in Paediatric Patients
Enrollment Status: Recruiting
Publish Date: March 19, 2026

Summary: This study evaluates the inter-observer reliability of a standardized WB-MRI scoring system for CRMO and its consistency with the PedCNO clinical score. It also investigates whether changes in the radiologic score mirror therapeutic response, supporting a more objective clinical-radiological disease assessment.

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Coordination of Rare Diseases at Sanford
Coordination of Rare Diseases at Sanford
Enrollment Status: Recruiting
Publish Date: May 29, 2025

Summary: CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, in...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center