Chronic Subdural Hematoma Clinical Trials

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Neuroendoscopy-assisted Drainage Versus Burr Hole Drainage for Chronic Subdural Hematoma: A Multicenter Randomized Controlled Trial, URANUS

Status: Recruiting
Location: See all (24) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Chronic subdural hematoma (CSDH) is a frequent condition in neurosurgery, leading to fluid accumulation between the meninges, brain compression, neurological dysfunction, and potentially herniation. The efficacy of treatments and their long-term outcomes remain uncertain, with no established standard. Notably, neuroendoscopy-assisted hematoma evacuation, in contrast to burr-hole drainage, enables direct visualization and thorough removal of the hematoma, thereby minimizing residue, lowering recurrence rates, and shortening drainage duration. This study will undertake a multicenter trial to compare these two methods and determine the superior treatment approach for CSDH.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:

• Patient (18 years to 90 years) presenting with clinical symptoms and neurological deficits of CSDH.

• CSDH verified on cranial computed tomography or magnetic resonance imaging.

• Written informed consent from patients or their next of kin according to the patient's cognitive status.

Locations
Other Locations
China
Beijing Tiantan Hospital, Capital Medical University
RECRUITING
Beijing
Changde First People's Hospital
RECRUITING
Changde
Heji Hospital affiliated with Changzhi Medical College
RECRUITING
Changzhi
Hebei University of Engineering Affiliated Hospital
RECRUITING
Handan
Jiangmen Central Hospital
RECRUITING
Jiangmen
People's Hospital of Xiangxi Prefecture, Hunan Province
RECRUITING
Jishou
Linfen People's Hospital
RECRUITING
Linfen
Liuzhou worker's Hospital
RECRUITING
Liuchow
Mianyang 404 Hospital
RECRUITING
Mianyang
Nanning First People's Hospital
RECRUITING
Nanning
The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine
RECRUITING
Nanning
The Second Affiliated Hospital of Guangxi Medical University
RECRUITING
Nanning
Pu'er People's Hospital
RECRUITING
Pu'er
Shantou central hosital
RECRUITING
Shantou
People's Hospital of Longhua, Shenzhen
RECRUITING
Shenzhen
Shanxi Provincial People's Hospital,Shanxi Medical University
RECRUITING
Taiyuan
First Affiliated Hospital of Xinjiang Medical University
RECRUITING
Ürümqi
First Affiliated Hospital of Wenzhou Medical University
RECRUITING
Wenzhou
Wuzhou Gongren Hospital
RECRUITING
Wuzhou
The Second Affiliated Hospital of Xi'an Medical University
RECRUITING
Xi’an
First Affiliated Hospital of Xiamen University
RECRUITING
Xiamen
Xingtai Central Hospital
RECRUITING
Xingtai
the First People'S Hospital of Yibin
RECRUITING
Yibin
Yueyang Central Hospital
RECRUITING
Yueyang
Contact Information
Primary
Liang Wu, MD
jasewl@sina.com
18301674233
Backup
Yu Yan, MB
2710575494@qq.com
13701141637
Time Frame
Start Date: 2025-11-19
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 770
Treatments
Experimental: Neuroendoscope-assisted hematoma drainage
Under the guidance of a visualized neuroendoscope, the hematoma is thoroughly irrigated and evacuated.
Other: Burr hole hematoma drainage
The hematoma cavity is irrigated intraoperatively until the drainage fluid becomes clear.
Sponsors
Leads: Beijing Tiantan Hospital

This content was sourced from clinicaltrials.gov