Condition 101 About Cicatricial Pemphigoid

What is the definition of Cicatricial Pemphigoid?

Mucous membrane pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. Other mucosal sites that might be affected include the nasopharnyx, larynx, genitalia, rectum, and esophagus. The condition usually begins in late adulthood (e.g. 50's or 60's), affects more women than men, and has a variable prognosis. Scarring of the affected  mucosa of the eye may lead to blindness and tends to be the most feared complication. A combination of environmental and genetic factors appear to play a role in the susceptibility of developing cicatricial pemphigoid. Although the specific causes of this condition have not been identified, it is considered an autoimmune disease that is characterized by the production of autoantibodies against basement membrane zone antigens such as BP180, BP230, and laminin 5.  Treatment is dependent on the person's specific symptoms.

What are the alternative names for Cicatricial Pemphigoid?

  • Benign mucosal pemphigoid
  • Benign mucous membrane pemphigoid
  • Cicatricial pemphigoid disease

Top Global Doctors For Cicatricial Pemphigoid

Latest Advances On Cicatricial Pemphigoid

  • Condition: Benign Mucous Membrane Pemphigoid
  • Journal: The Journal of dermatological treatment
  • Treatment Used: Rituximab
  • Number of Patients: 24
  • Published —
This study tested the safety and efficacy of using rituximab to treat patients with benign mucous membrane pemphigoid.
  • Condition: Corneal Diseases
  • Journal: Revue medicale de Liege
  • Treatment Used: Osteo-Odonto-Keratoprosthesis (OOKP)
  • Number of Patients: 0
  • Published —
This article discusses corneal diseases and their treatments.

Clinical Trials For Cicatricial Pemphigoid

Clinical Trial
  • Status: Not yet recruiting
  • Intervention Type: Diagnostic Test
  • Participants: 30
  • Start Date: December 1, 2020
Study of the Periodontal Microbiota in Gingival Cicatricial Pemphigoid Patients. Bicentric Pilot Study on 30 Patients.
Clinical Trial
  • Status: Recruiting
  • Intervention Type: Diagnostic Test
  • Participants: 300
  • Start Date: February 1, 2020
Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface