Cloacal Exstrophy Overview

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Learn About Cloacal Exstrophy

What is the definition of Cloacal Exstrophy?
OEIS complex, also known as cloacal exstrophy, is the most severe birth defect within the exstrophy-epispadias complex. It is characterized by Omphalocele, Exstrophy, Imperforate anus and Spinal defects. A child with this condition will have the bladder and a portion of the intestines exposed outside the abdomen with the bony pelvis open like a book. In males, the penis is either flat and short or sometimes split. In females, the clitoris is split and there may be two vaginal openings. Also, frequently the intestine is short and the anus is not open (anus imperforate). There is a high association with other birth defects, especially spina bifida, which occurs in up to 75% of cases. Omphalocele, a defect of the abdominal wall in the region of the umbilicus, is also common, as are kidney abnormalities. The defect occurs when the baby is developing inside the uterus during the first trimester of pregnancy, and seems to be due to the rupture of a tissue known as the cloacal membrane which results in the abnormal development of the abdominal wall and other malformations. The timing of the rupture determines the severity of the disorder. The cause for this malformation is unknown.
What are the alternative names for Cloacal Exstrophy?
  • Omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects complex
  • Cloacal exstrophy
  • Cloacal exstrophy sequence
  • OEIS complex
  • Omphalocele - cloacal exstrophy - imperforate anus - spinal defect
  • Omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects
  • Omphalocele-cloacal exstrophy-imperforate anus-spinal defect syndrome
Who are the top Cloacal Exstrophy Local Doctors?
Francis X. Schneck
Elite in Cloacal Exstrophy
Dr. Francis X. Schneck
Pediatrics
Elite in Cloacal Exstrophy
Dr. Francis X. Schneck
Pediatrics

Pediatric Urology In Lawrenceville

4401 Penn Avenue, 
Pittsburgh, PA 
412-692-7932
Languages Spoken:
English
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Accepting New Patients

Francis X. Schneck, MD, is a pediatric urologist and program director of the Pediatric Urology Fellowship Program at UPMC Children’s Hospital of Pittsburgh. He is also an associate professor of urology at the University of Pittsburgh School of Medicine. He earned his medical degree from the Georgetown University School of Medicine. He then completed a residency in Urology at the University of Pittsburgh School of Medicine and a pediatric urology fellowship at the Harvard Medical School and Children's Hospital. He joined UPMC upon completion of his fellowship. Dr. Schneck is the author of numerous articles and book chapters in the field of pediatric urology and is board certified by the American Board of Urology. View a list of Dr. Schneck's publications on PubMed. Are you already a patient of this provider and have a MyUPMC account? Log in to MyUPMC to schedule. Dr. Schneck is rated as an Elite provider by MediFind in the treatment of Cloacal Exstrophy. His top areas of expertise are Cloacal Exstrophy, UPJ Obstruction, Undescended Testicle, Orchiectomy, and Lithotripsy.

Elite in Cloacal Exstrophy
Dr. John P. Gearhart
Urology
Elite in Cloacal Exstrophy
Dr. John P. Gearhart
Urology

Johns Hopkins University

1800 Orleans St, 
Baltimore, MD 
410-955-5000
Languages Spoken:
English
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Accepting New Patients

John Gearhart is an Urologist in Baltimore, Maryland. Dr. Gearhart is rated as an Elite provider by MediFind in the treatment of Cloacal Exstrophy. His top areas of expertise are Cloacal Exstrophy, Exstrophy of the Bladder, Exstrophy-Epispadias Complex, Osteotomy, and Bladder Reconstruction. Dr. Gearhart is currently accepting new patients.

 
 
 
 
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Elite in Cloacal Exstrophy
Dr. Chad B. Crigger
Urology
Elite in Cloacal Exstrophy
Dr. Chad B. Crigger
Urology

Johns Hopkins University

600 N Wolfe St, Blalock 266, 
Baltimore, MD 
410-502-4340
Experience:
9+ years
Languages Spoken:
English
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Accepting New Patients

Chad Crigger is an Urologist in Baltimore, Maryland. Dr. Crigger has been practicing medicine for over 9 years and is rated as an Elite provider by MediFind in the treatment of Cloacal Exstrophy. His top areas of expertise are Exstrophy of the Bladder, Cloacal Exstrophy, Epispadias, Osteotomy, and Bladder Reconstruction. Dr. Crigger is currently accepting new patients.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center