Cloacal Exstrophy
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Cloacal Exstrophy Overview

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What is the definition of Cloacal Exstrophy?
OEIS complex, also known as cloacal exstrophy, is the most severe birth defect within the exstrophy-epispadias complex. It is characterized by Omphalocele, Exstrophy, Imperforate anus and Spinal defects. A child with this condition will have the bladder and a portion of the intestines exposed outside the abdomen with the bony pelvis open like a book. In males, the penis is either flat and short or sometimes split. In females, the clitoris is split and there may be two vaginal openings. Also, frequently the intestine is short and the anus is not open (anus imperforate). There is a high association with other birth defects, especially spina bifida, which occurs in up to 75% of cases. Omphalocele, a defect of the abdominal wall in the region of the umbilicus, is also common, as are kidney abnormalities. The defect occurs when the baby is developing inside the uterus during the first trimester of pregnancy, and seems to be due to the rupture of a tissue known as the cloacal membrane which results in the abnormal development of the abdominal wall and other malformations. The timing of the rupture determines the severity of the disorder. The cause for this malformation is unknown.
What are the alternative names for Cloacal Exstrophy?
  • Omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects complex
  • Cloacal exstrophy
  • Cloacal exstrophy sequence
  • OEIS complex
  • Omphalocele - cloacal exstrophy - imperforate anus - spinal defect
  • Omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects
  • Omphalocele-cloacal exstrophy-imperforate anus-spinal defect syndrome
Who are the top Cloacal Exstrophy Local Doctors?
Elite in Cloacal Exstrophy
Elite in Cloacal Exstrophy
Referral may be required
Tokyo, JP 

Masayuki Kubota practices practicing medicine in Tokyo, Japan. Mr. Kubota is rated as an Elite expert by MediFind in the treatment of Cloacal Exstrophy. He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Cloacal Exstrophy, Imperforate Anus, Kuster Syndrome, Pancreaticoduodenectomy, and Bladder Reconstruction.

Elite in Cloacal Exstrophy
Elite in Cloacal Exstrophy
Referral may be required

Johns Hopkins Children's Center

1800 Orleans St, 
Baltimore, MD 
410-955-4494
Experience:
10+ years
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Mahir Maruf is a Urologist practicing medicine in Baltimore, Maryland. He has been practicing medicine for over 10 years. Dr. Maruf is rated as an Elite provider by MediFind in the treatment of Cloacal Exstrophy. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Exstrophy of the Bladder, Exstrophy-Epispadias Complex, Cloacal Exstrophy, Bladder Reconstruction, and Osteotomy. Dr. Maruf is currently accepting new patients.

 
 
 
 
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Advanced in Cloacal Exstrophy
Advanced in Cloacal Exstrophy
Referral may be required
675 N St Clair St Ste 20-150, Galter Pavilion, 
Chicago, IL 
312-695-8146
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Diana Bowen is a Urologist practicing medicine in Chicago, Illinois. Dr. Bowen is rated as an Advanced provider by MediFind in the treatment of Cloacal Exstrophy. She is also highly rated in 15 other conditions, according to our data. Her clinical expertise encompasses Neurogenic Bladder, Myelomeningocele, Exstrophy of the Bladder, Orchiectomy, and Lithotripsy. Dr. Bowen is board certified in American Board Of Urology - Pediatric Urology (Certified). Dr. Bowen is currently accepting new patients.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center