Cold Urticaria Overview

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Learn About Cold Urticaria

What is the definition of Cold Urticaria?
Cold urticaria is an allergic condition that affects the skin. Symptoms usually start in early adulthood. The most common symptom is a red, itchy rash that appears on the skin when it is exposed to the cold (e.g. cold weather or cold water). This reaction usually occurs within 5-10 minutes after exposure and can last for 1-2 hours. The exact cause of Cold urticaria is unknown. In some cases, it may be associated with an infection, insect bite, or blood cancer. It is diagnosed based on the symptoms and confirmed through tests that look for a specific reaction to cold.
What are the alternative names for Cold Urticaria?
  • Cold urticaria
  • Cold contact urticaria
  • Primary idiopathic cold urticaria
  • Urticaria idiopathic cold
Who are the top Cold Urticaria Local Doctors?
Elite in Cold Urticaria
Dorothea Molawi-Terhorst
Elite in Cold Urticaria
Dorothea Molawi-Terhorst
Berlin, BE, DE 

Dorothea Molawi-Terhorst practices in Berlin, Germany. Ms. Molawi-Terhorst is rated as an Elite expert by MediFind in the treatment of Cold Urticaria. Her top areas of expertise are Cold Urticaria, Hives, Chronic Spontaneous Urticaria (CSU), and Angioedema.

Elite in Cold Urticaria
Mojca C. Bizjak
Elite in Cold Urticaria
Mojca C. Bizjak
Golnik, SI 

Mojca Bizjak practices in Golnik, Slovenia. Bizjak is rated as an Elite expert by MediFind in the treatment of Cold Urticaria. Their top areas of expertise are Cold Urticaria, Hives, Chronic Spontaneous Urticaria (CSU), and Anaphylaxis.

 
 
 
 
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Elite in Cold Urticaria
Jasmin B. Deschner-Kuemmerle
Elite in Cold Urticaria
Jasmin B. Deschner-Kuemmerle
Hoppe Seyler Str. 9, 
Tuebingen, BW, DE 

Jasmin Deschner-Kuemmerle practices in Tuebingen, Germany. Ms. Deschner-Kuemmerle is rated as an Elite expert by MediFind in the treatment of Cold Urticaria. Her top areas of expertise are Familial Cold Autoinflammatory Syndrome, Neonatal Onset Multisystem Inflammatory Disease, Muckle-Wells Syndrome, and Mevalonate Kinase Deficiency.

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What are the latest Cold Urticaria Clinical Trials?
A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Parallel-Group Study of Barzolvolimab in Participants With Cold Induced Urticaria and Symptomatic Dermographism (EMBARQ-COLDU and SD)
A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Parallel-Group Study of Barzolvolimab in Participants With Cold Induced Urticaria and Symptomatic Dermographism (EMBARQ-COLDU and SD)
Enrollment Status: Recruiting
Publish Date: December 15, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: The purpose of this Phase 3, randomized, double-blind, placebo-controlled study is to assess the activity and safety of barzolvolimab compared to placebo in participants with cold induced urticaria or symptomatic dermographism who remain symptomatic despite the use of H1-antihistamines.

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A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Tolerability, Pharmacokinetic, Pharmacodynamic, and Preliminary Efficacy Trial of GTX-B001 in Healthy Volunteers (Part A) and Patients With Cold Induced Urticaria (Part B)
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Tolerability, Pharmacokinetic, Pharmacodynamic, and Preliminary Efficacy Trial of GTX-B001 in Healthy Volunteers (Part A) and Patients With Cold Induced Urticaria (Part B)
Enrollment Status: Recruiting
Publish Date: December 04, 2025
Intervention Type: Drug
Study Phase: Phase 1

Summary: This is a first-in-human study aimed at determining the safety of a single dose of GTX-B001 in healthy participants and in people with cold urticaria.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center