The Prevalence of Local IgE Elevation and Its Effect on Intranasal Capsaicin Therapy in the Non-allergic Rhinitis Population

Who is this study for? Patients with Non-allergic Rhinitis
What treatments are being studied? Intranasal Capsaicin+Topical Lidocaine
Status: Completed
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The purpose of this study to determine the therapeutic response of non-allergic rhinitis patients that have been subtyped as non-allergic rhinitis with local IgE elevation or non-allergic rhinopathy to intranasal capsaicin based on visual analog scale and optical rhinometry, to determine the prevalence of non-allergic rhinitis with local IgE elevation in this study's cohort of patients with non-allergic rhinitis identified by rhinitis history and negative skin testing for allergic rhinitis, and to determine the change, if any, in intranasal IgE levels after capsaicin treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Chronic rhinitis

Locations
United States
Texas
The University of Texas Health Science Center at Houston
Houston
Time Frame
Start Date: 2019-09-10
Completion Date: 2023-11-30
Participants
Target number of participants: 28
Treatments
Experimental: Treatment
Authors
Baily A LeConte
Related Therapeutic Areas
Sponsors
Collaborators: American Academy of Otolaryngic Allergy
Leads: The University of Texas Health Science Center, Houston

This content was sourced from clinicaltrials.gov

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