A Multicentre, Randomised, Open Label, Parallel Group, Controlled Clinical Trial to Evaluate Efficacy and Tolerability of Two Seawater-based Formulations Plus a Standard of Care Versus the Standard of Care Alone for Relief of Nasal Congestion in Paediatric Subjects With Common Cold

Status: Terminated
Location: See location...
Intervention Type: Behavioral, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The objective of this clinical trial is to evaluate the tolerance and efficacy of two Stérimar nasal sprays products in children who have nasal congestion due to the common cold.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3 months
Maximum Age: 4
Healthy Volunteers: f
View:

• Male and female infants and toddlers aged 3 - 48 months (inclusive) at enrolment (Day 0).

• Caretaker(s) answering yes to the question Do you feel that your child has a cold? at enrolment (Day 0).

• Subjects with symptoms started within 48 hours prior to enrolment (Day 0).

• Subjects with nasal congestion (blocked / stuffy nose) rated as at least grade 2 (moderately bothersome) on a 0 to 2-point scale, based on morning evaluation (within an hour of subject awakening).

• Subjects showing at least grade 2 on a 0 to 2-point scale for at least one of the following additional signs of cold symptoms: runny nose, nasal crust (dry mucus), thick mucus, sneezing and cough.

• Legal caretaker(s) signed written informed consent for their young ones to participate in the study.

• Legal caretaker(s) willing to comply with all study procedures.

• Ability of the caretaker(s) (in the Investigator's opinion) to comprehend the full nature, procedures, and purpose of the study.

Locations
Other Locations
Italy
San Paolo Hospital
Milan
Time Frame
Start Date: 2021-11-25
Completion Date: 2023-03-20
Participants
Target number of participants: 9
Treatments
Experimental: Group A
IP1 - Stérimar BLOCKED NOSE Baby nasal spray + standard of care
Experimental: Group B
IP2 - Stérimar Stop \& Protect Cold Baby + standard of care
Other: Group C
Standard of Care alone
Related Therapeutic Areas
Sponsors
Leads: Church & Dwight Company, Inc.
Collaborators: Evidilya S.r.l.

This content was sourced from clinicaltrials.gov