Double-blind, Multicenter, Randomized, Placebo-controlled Study to Investigate the Efficacy, Safety and Tolerability of Ingavirin®, 60 mg Capsules in the Treatment of Influenza and Other Acute Respiratory Viral Infections in Children Aged 13-17 Years.

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The study is planned to evaluate the therapeutic efficacy and safety of Ingavirin®, capsules, 60 mg, in the treatment of influenza or other acute respiratory infections in children from 13 to 17 years compared with placebo.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 13
Maximum Age: 17
Healthy Volunteers: f
View:

• Male and female patients aged 13 to 17 years inclusive.

• Clinically established diagnosis of influenza or acute respiratory viral infection based on the presence of body temperature \> 37.5 °C and at least 1 of the following symptoms of intoxication syndrome, and at least 1 manifestation of catarrhal syndrome: symptoms of intoxication syndrome (headache, chills, weakness, brokenness, eyeball pain, nausea); catarrhal syndrome (sore throat, rhinitis, pharyngitis, laryngitis, cough).

• Laboratory-confirmed diagnosis of influenza or acute respiratory viral infections using one or more of the following viral antigen detection methods.

• Uncomplicated course of influenza or ARVI.

• Interval between the onset of the first symptoms of the disease and inclusion in the study no more than 36 h.

• Availability of an informed consent form signed by one of the parents (or legal representatives) of the child for participation in the study.

• For patients 14 years and older, a signed informed consent form for participation in the study.

Locations
Other Locations
Russian Federation
GBOU VPO Rostov State Medical University of Ministry of Health of Russian Federation
RECRUITING
Rostov-on-don
GBOU VPO Siberia State Medcial University of Ministry of Health of Russian Federation
RECRUITING
Tomsk
GBOU VPO Yaroslavl State Medical University of Ministry of Health of Russian Federation
RECRUITING
Yaroslavl
Time Frame
Start Date: 2023-12-19
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 80
Treatments
Experimental: Ingavirin®, capsules, 60 mg
Ingavirin® will be administered once a day (60 mg/day) for 5 days on top of standard therapy.
Placebo_comparator: Placebo
Placebo will be administered once a day for 5 days on top of standard therapy.
Related Therapeutic Areas
Sponsors
Leads: Valenta Pharm JSC

This content was sourced from clinicaltrials.gov