Real-life Performance and Added Value of the VIDAS® TBI Blood Test in the Assessment of Mild Traumatic Brain Injury (mTBI), in Subjects with a Glasgow Coma Scale (GCS) Between 13-15

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Decision Rules for an initial CT-scan in patients arriving to Emergency Department (ED) and presenting a mild traumatic brain injury could be optimized by the use of an objective parameter easily and rapidly measured. This may be the place for serum biomarkers providing a quick and accurate assessment. BioMérieux has now developed an automated assay for the measurement of serum Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin C-terminal Hydrolase (UCH-L1), the VIDAS® TBI assay to fill out this unmet needs. The goal of the herein study is to generate real-world data and evidences to support the VIDAS® TBI performances.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult subject ≥ 18 years old

• Subject with a Glasgow Coma Scale (GCS) score between 13-15 on admission

• Subject presenting to the Emergency Department for suspected mild Traumatic Brain Injury

• Subject with a non-contrast head Computed Tomography (CT) scan ordered per the clinical site's care usual care

• Blood sampling possible within 12 hours of injury (1 tube of 4-5 mL of blood)

• Subject expected to stay at least 2 hours in the ED or in a ward

• Subject with signed Informed Consent Form (ICF)

Locations
United States
Florida
Orlando Health
RECRUITING
Orlando
Michigan
Wayne State University
RECRUITING
Detroit
Minnesota
Mayo Clinic
RECRUITING
Rochester
Missouri
Washington University
RECRUITING
St Louis
New York
University of Rochester
RECRUITING
Rochester
Contact Information
Primary
bioMérieux Medical Affairs
clinicalstudies@biomerieux.com
+33 4 78 87 20 00
Time Frame
Start Date: 2024-05-16
Estimated Completion Date: 2025-11-16
Participants
Target number of participants: 900
Treatments
Experimental: Subjects with Mild Traumatic Brain injury
Subjects presenting to the ED within 12 hours of suspected mild head trauma and a Glasgow Score of 13-15 undergo to blood collection for VIDAS® TBI \[GFAP, UCH-L1\] testing.
Related Therapeutic Areas
Sponsors
Leads: BioMérieux

This content was sourced from clinicaltrials.gov