Learn About Congenital Hypothyroidism
Congenital hypothyroidism is a partial or complete loss of function of the thyroid gland (hypothyroidism) that affects infants from birth (congenital). The thyroid gland is a butterfly-shaped tissue in the lower neck. It makes iodine-containing hormones that play an important role in regulating growth, brain development, and the rate of chemical reactions in the body (metabolism). People with congenital hypothyroidism have lower-than-normal levels of these important hormones.
Congenital hypothyroidism can be caused by a variety of factors, only some of which are genetic. The most common cause worldwide is a shortage of iodine in the diet of the mother and the affected infant. Iodine is essential for the production of thyroid hormones. Genetic causes account for about 15 to 20 percent of cases of congenital hypothyroidism.
Congenital hypothyroidism affects an estimated 1 in 2,000 to 4,000 newborns. For reasons that remain unclear, congenital hypothyroidism affects more than twice as many females as males.
Most cases of congenital hypothyroidism are sporadic, which means they occur in people with no history of the disorder in their family.
Atrium Health Concierge Care Lake Norman
Christopher Messitt is a primary care provider, practicing in Family Medicine in Cornelius, North Carolina. Dr. Messitt is rated as a Distinguished provider by MediFind in the treatment of Congenital Hypothyroidism. His top areas of expertise are Transient Familial Hyperbilirubinemia, Thyroid Dysgenesis, Congenital Hypothyroidism, and Newborn Jaundice. Dr. Messitt is currently accepting new patients.
Juliane Leger practices in Paris, France. Ms. Leger is rated as an Elite expert by MediFind in the treatment of Congenital Hypothyroidism. Her top areas of expertise are Congenital Hypothyroidism, Neonatal Hypothyroidism, Hypothyroidism, Hormone Replacement Therapy (HRT), and Thyroidectomy.
Maria Vigone practices in Milan, Italy. Ms. Vigone is rated as an Elite expert by MediFind in the treatment of Congenital Hypothyroidism. Her top areas of expertise are Neonatal Hypothyroidism, Congenital Hypothyroidism, Hypothyroidism, Thyroidectomy, and Hormone Replacement Therapy (HRT).
Summary: The aim of this multicentric, randomised, two-arms and single-blinded clinical trial is to prospectively evaluate OptiThyDose for Congenital hypothyroidism (CH) and Graves' disease (GD).
Summary: Retro-prospective, exploratory, single-centre observational study conducted at the Endrocrine-Metabolic Diseases Centre of the Pediatrics Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy. The primary aim is to assess, by NGS sequencing of a panel of target genes, the frequency and type of variants with potential pathogenic significance in a patient population with congenital hypothy...
Published Date: September 01, 2015
Published By: National Institutes of Health