Congenital HypothyroidismSymptoms, Doctors, Treatments, Advances & More
Learn About Congenital Hypothyroidism
Congenital hypothyroidism is a partial or complete loss of function of the thyroid gland (hypothyroidism) that affects infants from birth (congenital). The thyroid gland is a butterfly-shaped tissue in the lower neck. It makes iodine-containing hormones that play an important role in regulating growth, brain development, and the rate of chemical reactions in the body (metabolism). People with congenital hypothyroidism have lower-than-normal levels of these important hormones.
Congenital hypothyroidism can be caused by a variety of factors, only some of which are genetic. The most common cause worldwide is a shortage of iodine in the diet of the mother and the affected infant. Iodine is essential for the production of thyroid hormones. Genetic causes account for about 15 to 20 percent of cases of congenital hypothyroidism.
Congenital hypothyroidism affects an estimated 1 in 2,000 to 4,000 newborns. For reasons that remain unclear, congenital hypothyroidism affects more than twice as many females as males.
Most cases of congenital hypothyroidism are sporadic, which means they occur in people with no history of the disorder in their family.
University Of Chicago Medical Center
Samuel Refetoff is an Endocrinologist practicing medicine in Chicago, Illinois. Dr. Refetoff is rated as an Elite provider by MediFind in the treatment of Congenital Hypothyroidism. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Hypothyroidism, Allan-Herndon-Dudley Syndrome, Congenital Hypothyroidism, and Generalized Resistance to Thyroid Hormone.
OHSU Hospital
Stephen Lafranchi is a Pediatric Endocrinologist practicing medicine in Portland, Oregon. Dr. Lafranchi is rated as an Elite provider by MediFind in the treatment of Congenital Hypothyroidism. He is also highly rated in 3 other conditions, according to our data. His clinical expertise encompasses Neonatal Hypothyroidism, Congenital Hypothyroidism, Short Stature (Growth Disorders), and Brachydactyly.
Atrium Health Concierge Care Lake Norman
Christopher Messitt is a primary care provider, practicing in Family Medicine in Cornelius, North Carolina. Dr. Messitt is rated as a Distinguished provider by MediFind in the treatment of Congenital Hypothyroidism. He is also highly rated in 5 other conditions, according to our data. His clinical expertise encompasses Transient Familial Hyperbilirubinemia, Thyroid Dysgenesis, Congenital Hypothyroidism, and Newborn Jaundice. Dr. Messitt is board certified in American Board Of Family Medicine. Dr. Messitt is currently accepting new patients.
Summary: Observational, retrospective, prospective, pharmacological, single-centre, non-profit study. The aim is to evaluate, in newborns diagnosed with Congenital Hypothyroidism, the medium- and long-term efficacy and safety of the new formulation of levothyroxine in oral solution, compared to the liquid drop formulation and the tablet formulation. The study will involve male and female patients referred ...
Summary: Retro-prospective, exploratory, single-centre observational study conducted at the Endrocrine-Metabolic Diseases Centre of the Pediatrics Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy. The primary aim is to assess, by NGS sequencing of a panel of target genes, the frequency and type of variants with potential pathogenic significance in a patient population with congenital hypothy...
Published Date: September 01, 2015
Published By: National Institutes of Health