Congenital Insensitivity to Pain with Anhidrosis Overview

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Learn About Congenital Insensitivity to Pain with Anhidrosis

What is the definition of Congenital Insensitivity to Pain with Anhidrosis?
Congenital insensitivity to pain with anhidrosis (CIPA) also known as hereditary sensory and autonomic neuropathy type IV, is an inherited disease where there is an inability to feel pain and temperature, and decreased or absent sweating (anhidrosis). The signs and symptoms of CIPA usually appear at birth or during infancy. The inability to feel pain and temperature often leads to repeated, severe injuries and unintentional self-injury is common. People with CIPA may also heal slowly from skin and bone injuries, which can lead to chronic bone infections (osteomyelitis) or a condition called Charcot joints. Absent sweating can cause recurrent, high fevers (hyperpyrexia) and seizures brought on by high temperature (febrile seizures). Other features may include dental caries, difficulty controlling urine and defecating (urine and fecal incontinence), behavioral or emotional problems and intellectual disability. CIPA is caused by changes in the NTRK1 gene. Inheritance is autosomal recessive.
What are the alternative names for Congenital Insensitivity to Pain with Anhidrosis?
  • Congenital insensitivity to pain with anhidrosis
  • CIPA
  • Familial dysautonomia, type 2
  • Familial dysautonomia, type II
  • HSAN 4
  • HSAN IV
  • HSNAN4
  • Hereditary sensory and autonomic neuropathy 4
  • Hereditary sensory neuropathy type IV
  • Insensitivity to pain, congenital, with anhidrosis
  • Neuropathy, congenital sensory, with anhidrosis
Who are the top Congenital Insensitivity to Pain with Anhidrosis Local Doctors?
Elite in Congenital Insensitivity to Pain with Anhidrosis
Ningbo Li
Elite in Congenital Insensitivity to Pain with Anhidrosis
Ningbo Li
No. 1095 Jie Fang Road, 
Wuhan, CN 

Ningbo Li practices in Wuhan, China. Li is rated as an Elite expert by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. Their top areas of expertise are Congenital Insensitivity to Pain with Anhidrosis, Anhidrosis, Hereditary Sensory and Autonomic Neuropathy Type 2, Hajdu-Cheney Syndrome, and Adenoidectomy.

Advanced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Michael A. Kelly
Neurology
Advanced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Michael A. Kelly
Neurology

Loyola University Medical Center

2160 S 1st Ave, 
Maywood, IL 
708-216-9000
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Michael Kelly is a Neurologist in Maywood, Illinois. Dr. Kelly is rated as an Advanced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. His top areas of expertise are Congenital Insensitivity to Pain with Anhidrosis, Hereditary Sensory and Autonomic Neuropathy Type 2, Infantile Axonal Neuropathy, and Stroke. Dr. Kelly is currently accepting new patients.

 
 
 
 
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Emily R. Jaeger
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Emily R. Jaeger
Neurology
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Emily R. Jaeger
Neurology

Aurora Neurology

200 E Ryan Rd, 
Oak Creek, WI 
414-570-3590
Languages Spoken:
English
See accepted insurances

Emily Jaeger is a Neurologist in Oak Creek, Wisconsin. Dr. Jaeger is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. Her top areas of expertise are Migraine, Seizures, Memory Loss, and Migraine with Brainstem Aura.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center