Congenital Insensitivity to Pain with Anhidrosis
Symptoms, Doctors, Treatments, Advances & More

Congenital Insensitivity to Pain with Anhidrosis Overview

Save information for later
Sign Up

Learn About Congenital Insensitivity to Pain with Anhidrosis

What is the definition of Congenital Insensitivity to Pain with Anhidrosis?
Congenital insensitivity to pain with anhidrosis (CIPA) also known as hereditary sensory and autonomic neuropathy type IV, is an inherited disease where there is an inability to feel pain and temperature, and decreased or absent sweating (anhidrosis). The signs and symptoms of CIPA usually appear at birth or during infancy. The inability to feel pain and temperature often leads to repeated, severe injuries and unintentional self-injury is common. People with CIPA may also heal slowly from skin and bone injuries, which can lead to chronic bone infections (osteomyelitis) or a condition called Charcot joints. Absent sweating can cause recurrent, high fevers (hyperpyrexia) and seizures brought on by high temperature (febrile seizures). Other features may include dental caries, difficulty controlling urine and defecating (urine and fecal incontinence), behavioral or emotional problems and intellectual disability. CIPA is caused by changes in the NTRK1 gene. Inheritance is autosomal recessive.
What are the alternative names for Congenital Insensitivity to Pain with Anhidrosis?
  • Congenital insensitivity to pain with anhidrosis
  • CIPA
  • Familial dysautonomia, type 2
  • Familial dysautonomia, type II
  • HSAN 4
  • HSAN IV
  • HSNAN4
  • Hereditary sensory and autonomic neuropathy 4
  • Hereditary sensory neuropathy type IV
  • Insensitivity to pain, congenital, with anhidrosis
  • Neuropathy, congenital sensory, with anhidrosis
Who are the top Congenital Insensitivity to Pain with Anhidrosis Local Doctors?
Elite in Congenital Insensitivity to Pain with Anhidrosis
Ningbo Li
Elite in Congenital Insensitivity to Pain with Anhidrosis
Ningbo Li
No. 1095 Jie Fang Road, 
Wuhan, CN 

Ningbo Li practices practicing medicine in Wuhan, China. Li is rated as an Elite expert by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. They are also highly rated in 6 other conditions, according to our data. Their clinical expertise encompasses Congenital Insensitivity to Pain with Anhidrosis, Anhidrosis, Hereditary Sensory and Autonomic Neuropathy Type 2, Hajdu-Cheney Syndrome, and Adenoidectomy.

Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Mohammad A. Khoshnoodi
Neurology
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Mohammad A. Khoshnoodi
Neurology

Reading Hospital

420 South 5th Avenue, 
West Reading, PA 
484-628-8000
Languages Spoken:
English
See accepted insurances

. Dr. Khoshnoodi is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. He is also highly rated in 13 other conditions, according to our data. His clinical expertise encompasses Peripheral Neuropathy, Miller-Fisher Syndrome, Guillain-Barre Syndrome, and Chronic Polyradiculoneuritis. Dr. Khoshnoodi is board certified in American Board Of Psychiatry And Neurology.

 
 
 
 
Learn about our expert tiers
Learn More
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Emily R. Jaeger
Neurology
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Emily R. Jaeger
Neurology

Aurora Neurology

200 E Ryan Rd, 
Oak Creek, WI 
414-570-3590
Languages Spoken:
English
See accepted insurances

Emily Jaeger is a Neurologist practicing medicine in Oak Creek, Wisconsin. Dr. Jaeger is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. She is also highly rated in 7 other conditions, according to our data. Her clinical expertise encompasses Migraine, Seizures, Memory Loss, and Migraine with Brainstem Aura. Dr. Jaeger is board certified in American Board Of Psychiatry & Neurology.

View All Doctors
What are the latest Congenital Insensitivity to Pain with Anhidrosis Clinical Trials?
Match to trials
Find the right clinical trials for you in under a minute
Get started
View All Clinical Trials
Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center