The CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH) 3.0 International Trial Consortium
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The primary objective of the STICH 3.0 Study is to determine whether CABG is superior to PCI in terms of all-cause mortality at 5 years in patients with severe CAD and iLVSD. Individual patient data from similar national RCTs independently powered for different efficacy endpoints will be pooled, harmonized, and analyzed. The primary endpoint is all-cause mortality.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age \>18 years
• LVEF ≤40%
• Extensive coronary artery disease (typically defined as a British Cardiovascular Intervention Society jeopardy score of ≥6, on a scale from 0 to 12, with higher scores indicating greater extent of disease).
Locations
Other Locations
Sweden
Dep of Cardiology, Sahlgrenska University Hospital
RECRUITING
Gothenburg
Contact Information
Primary
Björn Redfors, MD, PhD
bjorn.redfors@wlab.gu.se
+46 313421000
Backup
Mark Petrie, MD, PhD, Professor
Mark.Petrie@glasgow.ac.uk
+44 141 330 4558
Time Frame
Start Date: 2022-09-14
Estimated Completion Date: 2029-09-14
Participants
Target number of participants: 2800
Treatments
Experimental: Percutaneous Coronary Intervention (PCI)
Patients will be revascularized by PCI
No_intervention: Coronary artery bypass grafting (CABG)
Patients will be revascularized by CABG
Related Therapeutic Areas
Sponsors
Collaborators: Université de Montréal, Weill Medical College of Cornell University, Monash University, University of Leicester, Hannover Medical School, University of Glasgow, University of Oxford, Jena University Hospital, Yale University, University of Copenhagen, University of Groningen, Curtin University, University of Toronto
Leads: Vastra Gotaland Region