Evaluating the Long-term Health Consequences of COVID-19 and Rehabilitation Therapies to Speed Convalescence

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The proposed focuses on improving both morbidity and mortality in older Veterans and those recovering from COVID-19 by developing rehabilitation therapies to augment vascular endothelial function by combating the oxidative stress and inflammation associated with aging and further induced by COVID-19. The investigators expected outcomes will have an important positive impact because they will provide scientifically sound recommendations for rehabilitation to improve vascular endothelial function and minimize the long-term consequences of COVID-19.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: t
View:

• 50 years of age or greater

• Long-COVID and COVID-recovered patients must have SARS-CoV-19 positive test near the time of COVID-19 diagnosis

• Long-COVID and COVID-recovered patients must be 3-12 months post-initial COVID-19 diagnosis

• Ability to sign informed consent

Locations
United States
Utah
VA Salt Lake City Health Care System, Salt Lake City, UT
RECRUITING
Salt Lake City
Contact Information
Primary
Joel D Trinity, PhD
Joel.Trinity@va.gov
(801) 582-1565
Backup
Russell S Richardson, PhD
r.richardson@hsc.utah.edu
(801) 582-1565
Time Frame
Start Date: 2022-11-01
Estimated Completion Date: 2028-10-31
Participants
Target number of participants: 300
Treatments
Experimental: Exercise Rehabilitation
Participants will be assigned to the Exercise+Placebo or Exercise+Mito-Q rehabilitation interventions using block randomization (block size 10).
Placebo_comparator: Exercise Rehabilitation with Placebo
Participants will be assigned to Exercise+Placebo rehabilitation using block randomization (block size 10)
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development

This content was sourced from clinicaltrials.gov