Cowden Syndrome Overview
Learn About Cowden Syndrome
Cowden syndrome is a genetic disorder characterized by multiple noncancerous, tumor-like growths called hamartomas and an increased risk of developing certain cancers.
Changes in the PTEN, KLLN, or WWP1 gene are most commonly identified in people with Cowden syndrome or Cowden-like syndrome.
Although the exact prevalence of Cowden syndrome is unknown, researchers estimate that it affects about 1 in 200,000 people.
Cowden syndrome and Cowden-like syndrome are inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the condition and increase the risk of developing cancer. In some cases, an affected person inherits the mutation from one affected parent. Other cases may result from new mutations in the gene. These cases occur in people with no history of the disorder in their family.
Linda Hendricks practices in Nijmegen, Netherlands. Ms. Hendricks is rated as an Elite expert by MediFind in the treatment of Cowden Syndrome. Her top areas of expertise are Cowden Syndrome, Bannayan-Riley-Ruvalcaba Syndrome, Lhermitte-Duclos Disease, and Ruvalcaba Syndrome.
Nicoline Hoogerbrugge practices in Nijmegen, Netherlands. Ms. Hoogerbrugge is rated as an Elite expert by MediFind in the treatment of Cowden Syndrome. Her top areas of expertise are Lhermitte-Duclos Disease, Bannayan-Riley-Ruvalcaba Syndrome, Cowden Syndrome, Oophorectomy, and Salpingo-Oophorectomy.
Janneke Hoeijmakers-Schuurs practices in Nijmegen, Netherlands. Hoeijmakers-Schuurs is rated as an Elite expert by MediFind in the treatment of Cowden Syndrome. Their top areas of expertise are Cowden Syndrome, Bannayan-Riley-Ruvalcaba Syndrome, Lhermitte-Duclos Disease, and Ruvalcaba Syndrome.
Summary: NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll. If you are interested in clinical testing please consider seeing a local genetic counselor or other genetics professional. If you have already had clinical genetic testing and meet eligibility...
Summary: The purpose of this study is to evaluate the effectiveness of an adapted, telehealth functional behavioral therapy (FBTsIDD) specifically focused on promoting appropriate communication and behavioral strategies in individuals with syndromic intellectual and developmental disorders. Participants will be asked to complete virtual study assessments at intake and then on a monthly basis for the durati...
Published Date: March 03, 2021
Published By: National Institutes of Health