Cutaneous Lupus Erythematosus (CLE)
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Learn About Cutaneous Lupus Erythematosus (CLE)

What is the definition of Cutaneous Lupus Erythematosus (CLE)?
Cutaneous lupus erythematosus is a skin condition that usually occurs in individuals with systemic lupus erythematosus (SLE) but may appear before the disease becomes systemic. Systemic lupus erythematosus is an autoimmune disease in which the immune system attacks the skin, joints, kidneys, brain, and other organs. Cutaneous lupus erythematosus is categorized into three types: chronic cutaneous lupus erythematosus (CCLE), also known as discoid lupus erythematosus (DLE), subacute cutaneous lupus erythematosus (SCLE), and acute cutaneous lupus erythematosus (ACLE).
What are the symptoms of Cutaneous Lupus Erythematosus (CLE)?
Symptoms of chronic cutaneous lupus erythematosus, also known as discoid lupus erythematosus, are the appearance of disc-like lesions on the skin that are thick, scaly, block hair follicles, appear on skin exposed to the sun, and cause scarring. Symptoms of subacute cutaneous lupus erythematosus are the appearance of thick, scaly lesions on the skin that do not scar. Symptoms of acute cutaneous lupus erythematosus are lesions on the skin that are triggered by sun exposure.
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What are the current treatments for Cutaneous Lupus Erythematosus (CLE)?
Treatment for chronic cutaneous lupus erythematosus, also known as discoid lupus erythematosus, involves avoiding sun exposure; wearing Helioplex sunscreen with an SPF of 70 or higher; corticosteroid creams, ointments, and injections; anti-malarial medications, such as Plaquenil, hydroxychloroquine, or chloroquine; and/or immunosuppressive medications. Treatment for subacute cutaneous lupus erythematosus includes the use of sunscreen, wearing protective clothing when in the sun, and avoiding sun exposure. Subacute cutaneous lupus erythematosus is often resistant to treatment with steroids or anti-malarial medications. Acute cutaneous lupus erythematosus may be treated with prednisone or other immunosuppressive drugs, such as methotrexate, cyclosporine, azathioprine, or myco-phenolate mofetil.
Who are the top Cutaneous Lupus Erythematosus (CLE) Local Doctors?
Elite in Cutaneous Lupus Erythematosus (CLE)
Elite in Cutaneous Lupus Erythematosus (CLE)

Northwell Health Physician Partners Rheumatology At Great Neck

865 Northern Boulevard, Suite 302, 
Great Neck, NY 
Languages Spoken:
English

Richard Furie is a Rheumatologist practicing medicine in Great Neck, New York. Dr. Furie is rated as an Elite provider by MediFind in the treatment of Cutaneous Lupus Erythematosus (CLE). He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Lupus Nephritis, Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), and Discoid Lupus Erythematosus (DLE). Dr. Furie is board certified in American Board Of Internal Medicine and American Board Of Internal Medicine/Rheumatology.

Elite in Cutaneous Lupus Erythematosus (CLE)
Rheumatology
Elite in Cutaneous Lupus Erythematosus (CLE)
Rheumatology

Johns Hopkins Outpatient Center

Baltimore, MD 
Languages Spoken:
English, French

Michelle Petri, M.D. is a Professor of Medicine at the Johns Hopkins University School of Medicine. She attended medical school at Harvard University and fulfilled her internal medicine residency at the Massachusetts General Hospital. In addition, she completed two fellowship programs at the University of California, San Francisco in allergy and immunology and rheumatology. Dr. Petri is the Director of the Hopkins Lupus Cohort, a longitudinal study of morbidity and mortality in systemic lupus erythematosus, and Co-Director of the Hopkins Lupus Pregnancy Center. Dr. Petri is rated as an Elite provider by MediFind in the treatment of Cutaneous Lupus Erythematosus (CLE). She is also highly rated in 10 other conditions, according to our data. Her clinical expertise encompasses Lupus Nephritis, Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Tenotomy, and Osteotomy. Dr. Petri is board certified in American Board Of Internal Medicine and American Board Of Allergy And Immunology.

 
 
 
 
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Elite in Cutaneous Lupus Erythematosus (CLE)
Rheumatology
Elite in Cutaneous Lupus Erythematosus (CLE)
Rheumatology

Montefiore At AECOM

1300 Morris Park Avenue, 
Bronx, NY 
Languages Spoken:
English

Chaim Putterman, MD - Summary of Research Program and Goals. Dr. Putterman is rated as an Elite provider by MediFind in the treatment of Cutaneous Lupus Erythematosus (CLE). He is also highly rated in 7 other conditions, according to our data. His clinical expertise encompasses Lupus Nephritis, Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), and Vasculitis.

What are the latest Cutaneous Lupus Erythematosus (CLE) Clinical Trials?
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus

Summary: The goal of this clinical trial is to learn if VENT-03 works to treat patients with cutaneous lupus erythematosus (CLE) who may or may not have systemic lupus erythematosus (SLE). Another goal is to learn about the safety of VENT-03 and how it is processed by the body. The main questions it aims to answer are: * Does VENT-03 affect the activity and severity of CLE? * What side effects do participa...

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A Phase 3, Randomized, Double-Blind,Placebo-Controlled Parallel Study to Evaluate the Efficacy and Safety of Enpatoran in Participants With Active Cutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease Receiving Standard of Care (ELOWEN-1)

Summary: The purpose of this global, multicenter, Phase 3 study is to evaluate the efficacy and safety of enpatoran over 24 weeks in participants with active cutaneous manifestations of lupus erythematosus with or without systemic disease. Study details include: Study Duration: Up to 35 weeks. Treatment Duration: 24 weeks. Visit Frequency: every 4 weeks, with the exception of the Week 2 televisit. Study In...