Cutaneous Lupus Erythematosus (CLE)
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Learn About Cutaneous Lupus Erythematosus (CLE)

What is the definition of Cutaneous Lupus Erythematosus (CLE)?
Cutaneous lupus erythematosus is a skin condition that usually occurs in individuals with systemic lupus erythematosus (SLE) but may appear before the disease becomes systemic. Systemic lupus erythematosus is an autoimmune disease in which the immune system attacks the skin, joints, kidneys, brain, and other organs. Cutaneous lupus erythematosus is categorized into three types: chronic cutaneous lupus erythematosus (CCLE), also known as discoid lupus erythematosus (DLE), subacute cutaneous lupus erythematosus (SCLE), and acute cutaneous lupus erythematosus (ACLE).
What are the symptoms of Cutaneous Lupus Erythematosus (CLE)?
Symptoms of chronic cutaneous lupus erythematosus, also known as discoid lupus erythematosus, are the appearance of disc-like lesions on the skin that are thick, scaly, block hair follicles, appear on skin exposed to the sun, and cause scarring. Symptoms of subacute cutaneous lupus erythematosus are the appearance of thick, scaly lesions on the skin that do not scar. Symptoms of acute cutaneous lupus erythematosus are lesions on the skin that are triggered by sun exposure.
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What are the current treatments for Cutaneous Lupus Erythematosus (CLE)?
Treatment for chronic cutaneous lupus erythematosus, also known as discoid lupus erythematosus, involves avoiding sun exposure; wearing Helioplex sunscreen with an SPF of 70 or higher; corticosteroid creams, ointments, and injections; anti-malarial medications, such as Plaquenil, hydroxychloroquine, or chloroquine; and/or immunosuppressive medications. Treatment for subacute cutaneous lupus erythematosus includes the use of sunscreen, wearing protective clothing when in the sun, and avoiding sun exposure. Subacute cutaneous lupus erythematosus is often resistant to treatment with steroids or anti-malarial medications. Acute cutaneous lupus erythematosus may be treated with prednisone or other immunosuppressive drugs, such as methotrexate, cyclosporine, azathioprine, or myco-phenolate mofetil.
Who are the top Cutaneous Lupus Erythematosus (CLE) Local Doctors?
Elite in Cutaneous Lupus Erythematosus (CLE)
Elite in Cutaneous Lupus Erythematosus (CLE)
Referral may be required

Northwell Health Physician Partners Rheumatology At Great Neck

865 Northern Boulevard, Suite 302, 
Great Neck, NY 
Languages Spoken:
English

Richard Furie is a Rheumatologist practicing medicine in Great Neck, New York. Dr. Furie is rated as an Elite provider by MediFind in the treatment of Cutaneous Lupus Erythematosus (CLE). He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Systemic Lupus Erythematosus (SLE), Lupus Nephritis, Cutaneous Lupus Erythematosus (CLE), and Discoid Lupus Erythematosus (DLE). Dr. Furie is board certified in American Board Of Internal Medicine and American Board Of Internal Medicine/Rheumatology.

Elite in Cutaneous Lupus Erythematosus (CLE)
Rheumatology | Internal Medicine
Elite in Cutaneous Lupus Erythematosus (CLE)
Rheumatology | Internal Medicine
Referral may be required

Taubman Center

1500 E Medical Center Dr, Floor 3 Reception A, 
Ann Arbor, MI 
Languages Spoken:
English
Offers Telehealth

Dr. J. Michelle Kahlenberg MD, PhD is a physician scientist and Associate Professor of Internal Medicine at the University of Michigan. She completed her MD, PhD, and Internal Medicine training at Case Western Reserve University and completed her fellowship in Rheumatology at the University of Michigan. She joined the University of Michigan faculty in 2011, was appointed Assistant Professor in 2012, and was promoted to Associate Professor with tenure in 2018. She has been running her own laboratory and has been an active member of the Immunology Training Program since 2013. Her clinical work is centered on the care of complicated lupus patients, including those with refractory skin disease. Her R01-funded research laboratory combines translational approaches using patient samples and murine models to uncover the mechanisms that drive lupus and lupus flares. In particular, she is focused on unraveling the pathogenic mechanisms in cutaneous lupus, the factors that drive photosensitivity, and how skin inflammation can influence systemic lupus activity. Her work has received institutional accolades and national recognition from the Arthritis National Research Foundation, The Rheumatology Research Foundation, American Society for Clinical Investigation and the Lupus Foundation of America. In her spare time, she enjoys organic gardening, working on the family farm EMMA Acres run by her husband, Mark, and spending time with her husband and children. Dr. Kahlenberg is rated as an Elite provider by MediFind in the treatment of Cutaneous Lupus Erythematosus (CLE). She is also highly rated in 26 other conditions, according to our data. Her clinical expertise encompasses Cutaneous Lupus Erythematosus (CLE), Systemic Lupus Erythematosus (SLE), Discoid Lupus Erythematosus (DLE), and Mevalonate Kinase Deficiency. Dr. Kahlenberg is board certified in Rheumatology.

 
 
 
 
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Elite in Cutaneous Lupus Erythematosus (CLE)
Elite in Cutaneous Lupus Erythematosus (CLE)
Referral required

Brigham Dermatology Associates

221 Longwood Avenue 1st Floor Brigham And Women's At 221 Longwood Boston, 1st Floor Brigham And Women's At 221 Longwood, 
Boston, MA 
Languages Spoken:
English
Offers Telehealth

Ruth Vleugels is a Dermatologist practicing medicine in Boston, Massachusetts. Dr. Vleugels is rated as an Elite provider by MediFind in the treatment of Cutaneous Lupus Erythematosus (CLE). She is also highly rated in 26 other conditions, according to our data. Her clinical expertise encompasses Dermatomyositis, Discoid Lupus Erythematosus (DLE), Eosinophilic Fasciitis, and Cutaneous Lupus Erythematosus (CLE). Dr. Vleugels is board certified in Dermatology.

What are the latest Cutaneous Lupus Erythematosus (CLE) Clinical Trials?
A Randomized, Double-blind, Placebo-controlled Phase II Study to Evaluate the Efficacy and Safety of Oral ICP-488 in Subjects With Cutaneous Lupus Erythematosus (CLE)

Summary: This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical study to evaluate the efficacy and safety of ICP-488 in subjects with cutaneous lupus erythematosus (CLE).

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