Clinical Significance of Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)
Status: Recruiting
Location: See location...
Intervention Type: Genetic
Study Type: Observational
SUMMARY
AISRNA is to analyze the expression pattern of circular RNA (circRNA), micro-RNA (miRNA) and long non-coding RNA (lncRNA) by next-generation sequencing in patients with acute ischemic stroke and healthy control. The candidate circRNA/miRNA/lncRNA will be verified as biomarkers for the detection and prognosis of acute ischemic stroke.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Aged 18 years or older
• Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan
• Within 72 hours of symptom onset
• Good performance status
• Signed an approved informed consents
Locations
Other Locations
China
Nanjing First Hospital, Nanjing Medical University
RECRUITING
Nanjing
Contact Information
Primary
Junshan Zhou, M.D.
zhjsh333@126.com
+8602587726218
Backup
Qiwen Deng, M.D.
qiw_deng@163.com
+8602587726218
Time Frame
Start Date: 2019-11-24
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 500
Treatments
AIS group
This group includes patients with acute ischemic stroke (AIS).
HC group
This group includes healthy controls (HC).
Related Therapeutic Areas
Sponsors
Leads: Nanjing First Hospital, Nanjing Medical University