Early Antiplatelet Therapy After Hemorrhagic Infarction in Acute Ischemic Stroke Treated With Intravenous Thrombolysis in China (HITs):a Randomized Clinical Trial

Who is this study for? Patients with Hemorrhagic Infarction
What treatments are being studied? Aspirin
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

Previous study showed that the proportions of hemorrhagic Infarction after intravenous thrombolysis were 24.2% and 32.5% in the control group and the alteplase group, and most of them were asymptomatic. Hemorrhagic Infarction was a part of the natural progression after acute ischemic stroke. Previous study have shown no significant relationship between hemorrhagic Infarction and poor outcome in acute ischemic stroke (AIS) patients. In this study, a randomized controlled trial will be conducted to explore the efficacy and safety of early antiplatelet therapy after hemorrhagic infarction in acute ischemic stroke treated with intravenous thrombolysis.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Acute ischemic patients receiving intravenous thrombolysis within 24 hours upon stroke onset

• Be confirmed as Hemorrhagic Infarction at 24 to 36 hours after intravenous thrombolysis by computerized tomography

• The patient or family member signed an informed consent

Locations
Other Locations
China
the second affiliated hospital of Zhejiang University
RECRUITING
Hangzhou
Contact Information
Primary
Min Lou, PhD
loumingxc@vip.sina.com
+8657187784810
Time Frame
Start Date: 2021-01-01
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 294
Treatments
Active_comparator: Early Antiplatelet Therapy
Placebo_comparator: Non-Early Antiplatelet Therapy
Related Therapeutic Areas
Sponsors
Collaborators: Jinhua Central Hospital, The Affiliated Hospital of Xuzhou Medical University, Huzhou Central Hospital, Ningbo Medical Center Lihuili Hospital, Ningbo No.2 Hospital, Shaoxing People's Hospital, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, Taizhou Hospital, Lishui Country People's Hospital, Shenzhen Second People's Hospital, Wenzhou Central Hospital, The Second Affiliated Hospital of Jiaxing University, Affiliated Hospital of Jiaxing University
Leads: Second Affiliated Hospital, School of Medicine, Zhejiang University

This content was sourced from clinicaltrials.gov