Brain and Behavioral Responses to Backward Walking Training Post-Stroke

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Approximately 15,000 Veterans are hospitalized for stroke each year with new cases costing an estimated $111 million for acute inpatient, $75 million for post-acute inpatient, and $88 million for follow-up care over 6 months post-stroke. The investigators have previously established the effectiveness of a backward walking training program to improve gait and balance in post-stroke Veterans. To best serve Veterans in this era of personalized medicine, there is a current need to determine the appropriate training dose as well as which post-stroke Veterans would most benefit. This study addresses both needs as it will 1) test responses to two different doses (18 vs. 27 sessions) of backward walking training and 2) assess brain activity, measured by magnetic resonance imaging, before and after training intervention to determine its ability to predict rehabilitation response as well as brain mechanisms of behavioral change.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:

• Berg Balance Scale \< 45

• Self-selected 10 meter gait speed \< 0.8 m/s

• Diagnosis of unilateral stroke

• \> 2 months \< 4 months post-stroke

• Able to ambulate at least 10 feet with maximum 1 person assist

• Medically stable

Locations
United States
Florida
North Florida/South Georgia Veterans Health System, Gainesville, FL
RECRUITING
Gainesville
Brooks Rehabilitation
NOT_YET_RECRUITING
Jacksonville
Contact Information
Primary
Dorian K Rose, PhD MS BS
Dorian.Rose@va.gov
(352) 273-8307
Time Frame
Start Date: 2021-11-08
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 48
Treatments
Experimental: 27 session group
Participants in this arm will receive 27 sessions of backward walking training.
Active_comparator: 18 session group
Participants in this arm will receive 18 sessions of backward walking training.
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development

This content was sourced from clinicaltrials.gov